Don't overlook the SchoolTool Project (Score 2, Informative)

http://www.schooltool.org/ The project is funded by the Shuttleworth Foundation and consists of administation infrastructure, student information system and skills tracking programs. It's built on Zope3 and is part of the Ubuntu distribution (comes bundled with the Edubuntu variant by default). Very well built and well conceived software. It's getting more attention in Europe right now, but there are plenty of US users. I think the skills assessment part was built for Virginia schools.