Better Jukebox Software for Bigger Libraries?

jimjenkins1975 writes: I recently ripped and encoded my entire CD and Vinyl library, as well as merged my home and work computer's libraries (I work at a music company so my work library is very very large). It resulted in well over 750 GB of MP3's. I was hoping to get away with using iTunes to manage this, however the XML database file has grown very large, and the application itself is nonresponsive or very sluggish at best once it has loaded up (a process that takes several minutes itself) Question: Is there another application with similar features out there that can handle a library of this size with aplomb? I'm primarily on a Mac, and would prefer to keep using it, but I have a PC as well. Any ideas?