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Biotech

DNA Differences Observed Between Blood and Organs 85

Scrameustache writes "Researcher working on a rare type of aortic abnormality found that the DNA from diseased tissue did not match the DNA from the blood of the same patients So far it's unclear whether these differences in the blood and aortic tissue are the consequence of RNA editing, which changes the messenger RNA but not the gene, or DNA editing, which involves differences in the gene itself. Based on the evidence so far, the researchers believe the differences resulted from developmental rather than somatic DNA alterations. 'Traditionally when we have looked for genetic risk factors for, say, heart disease, we have assumed that the blood will tell us what's happening in the tissue,' lead author Bruce Gottlieb said in a statement. 'It now seems this is simply not the case.'"
Google

Google Apps Leave Beta 116

Today Google announced that they're removing the "beta" label from Gmail, Google Calendar, Google Docs and Google Talk. They said, "We've come to appreciate that the beta tag just doesn't fit for large enterprises that aren't keen to run their business on software that sounds like it's still in the trial phase." Quoting the NYTimes: "'Obviously we haven't had a consistent set of policies or definitions around beta,' said Matt Glotzbach, a director of product management at Google. Mr. Glotzbach said that different teams at Google had different criteria for what beta meant, and that Google felt a need to standardize those. ... Practically speaking, the change will mean precious little to Gmail's millions of users. But it could help Google's efforts to get the paid version of its package of applications, which includes Gmail, Calendar, Docs and other products, adopted inside big companies."
The Courts

Safe Harbor Spells Win For Kaspersky In Malware Case Against Zango 93

suraj.sun writes to tell us that the 9th Circuit Court of Appeals has ruled in favor of security company Kaspersky in the recent case questioning their classification of Zango software as malware. "The court ruled that Kaspersky Lab, which classified online media company Zango's software as malware and 'protected' users from it accordingly, could not be held liable for any actions it took to manufacture and distribute the technical means to restrict Zango software's access to others, as Kaspersky Lab deemed it 'objectionable material.' Zango sued Kaspersky Lab to force the Company to reclassify Zango's programs as nonthreatening and to prevent Kaspersky Lab's security software from blocking Zango's potentially undesirable programs. In the precedent-setting ruling for the anti-malware industry, the Court of Appeals for the Ninth Circuit affirmed a lower court ruling that Kaspersky Lab is a provider of an 'interactive computer service' as defined in the Communications Decency Act of 1996 . Part of the Communications Decency Act of 1996 states: 'No provider or user of an interactive computer service shall be held liable on account of ... any action taken to enable or make available to information content providers or others the technical means to restrict access to [objectionable] material.'"
Networking

How Demigod's Networking Problems Were Fixed 65

The launch of Demigod was troubled by piracy and networking difficulties, which publisher Stardock worked quickly to correct. They've now released a documentary that gives a detailed look behind the scenes of diagnosing and fixing those problems. It includes meetings, interviews with the devs, and part of the bug-tracking process during a frenzied 108-hour work week.

Comment Re:iPod not the first MP3 player (Score 1) 464

While we're on the topic, does anyone know how to fix a semi-bricked Creative Zen Vision M? :P Mine's got some stupid charging problem, it runs OK when I plug it in but it won't charge. :/

you might want to look at http://www.anythingbutipod.com/forum/forumdisplay.php?f=19 for your answers. I swapped the battery in my Creative Zen Touch with suggestions from that forum.

Math

New Pattern Found In Prime Numbers 509

stephen.schaubach writes "Spanish Mathematicians have discovered a new pattern in primes that surprisingly has gone unnoticed until now. 'They found that the distribution of the leading digit in the prime number sequence can be described by a generalization of Benford's law. ... Besides providing insight into the nature of primes, the finding could also have applications in areas such as fraud detection and stock market analysis. ... Benford's law (BL), named after physicist Frank Benford in 1938, describes the distribution of the leading digits of the numbers in a wide variety of data sets and mathematical sequences. Somewhat unexpectedly, the leading digits aren't randomly or uniformly distributed, but instead their distribution is logarithmic. That is, 1 as a first digit appears about 30% of the time, and the following digits appear with lower and lower frequency, with 9 appearing the least often.'"
Medicine

Submission + - Court Rules Autism Not Caused by Childhood Vaccine

wiredog writes: From The Washington Post comes word that three special masters have decided that MMR vaccines do not cause autism.

special master George Hastings said the parents ... had "been misled by physicians who are guilty, in my view, of gross medical misjudgment." ... "the evidence advanced by the petitioners has fallen far short of demonstrating . . . a link."

Games

An Early Look At Prince of Persia 13

Joystiq reports that work on Ubisoft's re-imagined Prince of Persia is complete, and the game has been sent off for certification leading up to its scheduled December 2nd launch. They were able to get some hands-on time with the game, and they have nothing but praise for the controls and the combat system. Quoting: "The game walked us through several fights' worth of control tutorial until we honestly didn't have to give second thought to what button we were pressing to execute a particular move. By the time we wrapped up our play session, we were sliding between enemies' legs, tossing them into the air, calling in Elika to teleport-kick them, and thwacking away until they teetered on the edges of cliffs — just before we delivered a final blow that sending them plummeting. What was doubly impressive about the combat system was the fact that, according to Delbuquet, it continues to evolve steadily throughout the course of the game. We were already stringing together our own combos at this point; nothing felt canned."
Communications

Net Neutrality Vets Join Obama FCC Transition Team 179

circleid writes "The Obama-Biden transition team on Friday named two long-time net neutrality advocates to head up its Federal Communications Commission Review team. Susan Crawford, a professor at the University of Michigan Law School, member of the board of directors of ICANN, and OneWebDay founder, as well as Kevin Werbach, former FCC staffer, organizer of the annual Supernova technology conference, and a Wharton professor, will lead the Obama-Biden transition team's review of the FCC. 'Both are highly-regarded outside-the-Beltway experts in telecom policy, and they've both been pretty harsh critics of the Bush administration's telecom policies in the past year.' The choice of the duo strongly signals an entirely different approach to the incumbent-friendly telecom policy-making that's characterized most of the past eight-years at the FCC." Reuters has a related story about Senator Byron Dorgan (D-ND), who plans to introduce net neutrality legislation in January.
Image

New "MP3 100% Compatible" Logo For DRM-Free Music 263

Sockatume writes "A coalition of seven UK digital music stores have created a logo for DRM-free, MP3 music. The 'MP3: 100% Compatible' logo allows the stores to emphasize the advantages of the format, namely that MP3 files will run on any device and won't keel over and die as DRM-laden files are wont to. The BPI — the UK equivalent of the RIAA — is backing the scheme, emphasizing that it will also allow users to identify legitimate stores."
Businesses

Amazon Launches "Frustration-Free Packaging" 353

mallumax notes Amazon's new Frustration-Free Packaging initiative. Over several years the retailer hopes to convince many of its suppliers to offer consumer-friendlier packaging. It's starting with just 19 products from Mattel, Fisher-Price, Microsoft, and Transcend. Until this program spreads to more products, better get one of these (ThinkGeek and Slashdot share a corporate overlord). From Amazon's announcement: "The Frustration-Free Package is recyclable and comes without excess packaging materials such as hard plastic clamshell casings, plastic bindings, and wire ties. It's designed to be opened without the use of a box cutter or knife and will protect your product just as well as traditional packaging. Products with Frustration-Free Packaging can frequently be shipped in their own boxes, without an additional shipping box. Amazon works directly with manufacturers to box products in Frustration-Free Packages right off the assembly lines, which reduces the overall amount of packing materials used."
Education

Discuss the US Presidential Election & Education 1515

In 24 hours, many of you will be able to vote. So as we come down to the wire, this is really our last chance to talk about the issues. We've already discussed Health Care, the War, and the Economy. Today I'm opening up the floor to discuss education. Perhaps no other issue will matter more in 50 years. Which candidate will make the next generation smarter?
Games

Stardock Evaluates DRM Complaints, Updates Gamer's Bill of Rights 279

Earlier this year, we discussed the Gamer's Bill of Rights, a document put forth by Stardock CEO Brad Wardell to address what he felt were the unacceptable characteristics of the gaming industry. ShackNews reports that Wardell has taken feedback from gamers, developers, and publishers, and updated the document accordingly. One particular area on which he focused was DRM. Stardock also published a customer report that examines the issue in greater detail (PDF). MTV's Multiplayer Blog fans the flames of the debate by asking if anyone is embarrassed about pirating video games.
Games

Dead Space Wants To Scare You 195

Kotaku recently ran a story questioning whether the survival-horror genre still exists, and how Dead Space may or may not fit into it. With reviews for the game starting to come in, Ars Technica reports that the game is, indeed, both scary and good. Gamespy wrote up a Dead Space survival guide, and Gamasutra has a lengthy interview with the game's senior producer. In the production of the game, the developers studied things like car wrecks and war scenes to increase the level of realism. They also want the game's sounds to terrify players, including appropriately timed silence. The launch trailer is also available, though it does contain spoilers.

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