Ian Lamont writes "Microsoft recently updated ESP, a virtual reality modeling platform that until now has primarily been used to model aircraft and flight simulations. Microsoft has plans to expand it to other industries such as real estate and urban planning, but one of the most interesting possibilities could be what one observer refers to as a 'simulation of everything,' based on Virtual Earth and perhaps even user-generated content. Indeed, Microsoft's research chief has been promoting the idea of commerce applications and other tools built on top of what he calls the 'Spatial Web', a blend of 3D, video, and location-aware technologies. He gave an example of a shopkeeper creating 3D models of his store's interior and goods with Photosynth and then uploading the results into a large 3D model of local shopping district. Customers could 'visit' the area, browse products, and order them for real-world delivery."

Anti-Globalism sends in this quote from Scientific American about attempts to synthesize molecules that function as well or better than the natural building blocks of life: "A molecule that some researchers study in pursuit of this vision is peptide nucleic acid (PNA), which mimics the information-storing features of DNA and RNA but is built on a proteinlike backbone that is simpler and sturdier than their sugar-phosphate backbones. ... Many studies have demonstrated PNA's suitability for modifying gene expression, mostly in molecular test-tube experiments and in cell cultures. Studies in animals have begun, as has research on ways to transform PNA into drugs that can readily enter a person's cells from the bloodstream. ... Some scientists have suggested that PNAs or a very similar molecule may have formed the basis of an early kind of life at a time before proteins, DNA and RNA had evolved. Perhaps rather than creating novel life, artificial-life researchers will be re-creating our earliest ancestors."

Bethesda has announced that an editor for the Windows version of Fallout 3 will be coming in December. They also said the first additional downloadable content for the Windows and XBox 360 versions will follow in January. MTV's Multiplayer blog got a few more details from Bethesda's Pete Hines, who said additions to Fallout 3 will resemble the Oblivion expansion pack Knights of the Nine in size and scope. MTV then brought up the question of how early publishers should provide DLC, pointing to Fallout 3 and Fable II as examples of games for which the expansions were planned to go live only a few months after launch.

destinyland writes "For decades, people have been asking this brain teaser: 'What's the longest word you can type with only the left-hand letters on a keyboard?' The answer is supposed to be 'stewardesses,' but grepping the standard dictionary that ships with Unix reveals a much better answer. There's nearly 2,000 shorter words that can typed with only the left hand — including one word that's even longer. (The article also quotes a failed novel attempt using nothing but words typed on the keyboard's left side.)"

A 60-year-old British woman is suffering from a neurological defect that is sure to put her in the next version of "The Man who Mistook His Wife for a Hat." She is unable to recognize any voice she hears — any voice, that is, but Sean Connery's. Unless she sees the face of the person speaking, she has no idea who is talking to her, even her daughter and co-worker's voices are unrecognizable. Dr. Brad Duchaine at University College London, thinks she might have the first documented case of vocal prosopagnosia, a condition which makes it extremely difficult for people to recognize faces. "His accent is distinctive," Duchaine explained. "And she is a British woman in her sixties ... let's say it's probable he got her attention."

New research has discovered some of the genetic changes that allowed vampire bats to live on a diet of pure blood. One of the bats' most important evolutionary traits is the ability to manipulate an anticoagulant protein in their blood and saliva. In humans similar proteins protect against heart attack by breaking up blood clots and clearing vessels.