I recently purchased the Asus EEE PC 4GB Surf, and after a few months of using Xandros with KDE, I installed Debian testing on it and decided to give GNOME a try. For some reason, GNOME was very slow compared to KDE. For example, movies were freezing constantly and games such as Open Arena, which worked flawlessly with KDE, were slow as hell.
So I removed GNOME, installed KDE, and the EEE was fast again...
I was interested with this and decided to give GNOME a try on my desktop computer. I reinstalled the entire distribution (Debian unstable) and installed GNOME. Just like in the EEE, it was slow, laggy, freezy and all sorts of words that convey this obvious meaning. After removing GNOME and installing KDE, everything was going fast and I was happy again.
So no, I guess I won't give GNOME another try.