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Comment We are already on our way to doing it! (Score 1) 409

by fain0v (#40843441) Attached to: Australian Billionaire Wants To Build Jurassic Park-Style Resort

Step 1: Sequence the genomes of every animal on the planet.
Step 2: Determine computationally how these animals diverged and back calculate a viable ancestor genomes.
Step 3: Build synthetic genomes of those animals that are viable.
Step 4: Transfer those genomes wrapped around histones with the correct modifications back into the an egg.

The technical problems are things like DNA methylation, back calculating genomes, and the fact that we don't know how most non-coding RNA works for organism development.
I'm sure I left out a bunch of stuff but we are currently developing the technology to do all these steps!

Comment Re:Mouse != Human (Score 1) 330

by fain0v (#39483727) Attached to: Drug Turns Immune System Against All Tumor Types

    I'd prefer that stuff like this stay firmly in the scientific process, and not put out the press release until they have done enough testing to be reasonably sure of the result.

It was a paper and the press release was from a scientific journal. The purpose is to get the information out to people that are curious or directly involved with related research. I read the intro and discussion and noticed calreticulin. I cloned that protein for someone and I just forwarded the article to him. I would never have have noticed it if it were not on slashdot.
Image

German Kindergartens Ordered To Pay Copyright For Songs 291

Posted by samzenpus from the easy-as-taking-music-from-a-baby dept.
BBird writes "Deutsche Welle reports: 'Up until this year, preschools could teach and produce any kind of song they wanted. But now they have to pay for a license if they want children to sing certain songs. A tightening of copyright rules means kindergartens now have to pay fees to Germany's music licensing agency, GEMA, to use songs that they reproduce and perform. The organization has begun notifying creches and other daycare facilities that if they reproduce music to be sung or performed, they must pay for a license.'"
Facebook

How Zynga's CityVille Drew 70 Million Players In Less Than a Month 101

Posted by Soulskill from the none-of-us-are-as-dumb-as-all-of-us dept.
An article at Gamasutra takes an in-depth look at how Zynga's new browser-based social game CityVille managed to accumulate tens of millions of players in the relatively short time since its launch early this month. Quoting: "The Facebook interface induces a high degree of user blindness. It does not do a great job of exposing new games and applications, and lacks a directory or a 'Featured in the App Store' style of editorial (as Apple does for the iPhone), which means that for most developers there are huge problems in getting their games in front of users' eyeballs. With all of the free advertising channels on the platform now constrained or dead, this has meant that the Facebook economy has been acquiring an increasingly Darwinian shape. Where it used to be an egalitarian environment in which any developer could strike it big, over the last year it has become top-heavy with larger developers accruing exponential success, and cutting off oxygen to smaller companies by default."

Comment Are antioxidants really what make vegetables good? (Score 1) 371

by fain0v (#34608936) Attached to: Free Radicals May Not Be Cause of Aging

I have thought about this problem for a long time now. Does the oxidative damage occur first causing aging or does aging lead a reduction in the cell's ability to combat oxidative stress?

A lab at the University of Michigan has done some great work on this, but the still have not quite answered the question.
http://www.mcdb.lsa.umich.edu/labs/jakob/scerevisiae.html

My opinion for a long time follows the article. I don't think that antioxidants from foods prevent DNA damage. I think that fruits and vegetables actually have compounds that are potentially carcinogens, and your body's oxidative stress response is upregulated by these. Yeast cells that are challenged with a low does of an oxidant are better able to handle a higher dose of oxidant than cells that were not. It's akin to whatever doesn't kill you makes you stronger.

Bruce Ames who invented the ames test to determine the mutagenic potential of compounds has published articles about how natural carcinogens are just as common as synthetic ones. Plants produce many of their own pesticides which have been shown to be carcinogens. I would highly recommend reading about this for any of you are into organic food choices.

So, fruits and vegetables help us live longer, but possibly by exactly the opposite reason that everyone believes.
Image

Aussie Gamers Dress As Zombies To Raise R18+ Awareness 85

Posted by samzenpus from the know-we'll-get-to-common-ground-somehow dept.
swandives writes "Australian gamers will dress as zombies to raise awareness about the lack of an R18+ rating for video games in the country. The protest will begin at Hyde Park Fountain on March 27 and lumber through Sydney, raising awareness of the need for a higher classification rating and hopefully causing a bit of havoc at the same time! Computerworld Australia has pictures of previous zombie protests in the lead-up to the event. Australia has a long history of lobbying for an R18+ games classification but, even after a decade, video games are banned from sale if they exceed the maximum M15+ classification. So far, the list of banned titles includes 7 Sins, Risen, Left 4 Dead 2 and Dark Sector. Others, like Alien vs. Predator, were initially banned but appealed the rating and are now MA15+."
Image

Officers Lose 243 Homeland Security Guns 125

Posted by samzenpus from the they-were-right-here-a-second-ago dept.
In a screw up so big it could only be brought to you by the government or a famous athlete, 243 guns were lost by Homeland Security agencies between 2006 and 2008. 179 guns, were lost "because officers did not properly secure them," an inspector general report said. One of the worst examples of carelessness cites a customs officer who left a firearm in an idling vehicle in the parking lot of a convenience store. The vehicle was stolen while the officer was inside. "A local law enforcement officer later recovered the firearm from a suspected gang member and drug smuggler," the report said.
Australia

Nintendo Wins Lawsuit Over R4 Mod Chip Piracy 146

Posted by Soulskill from the sorry-about-your-luck dept.
schliz writes "The Federal Court has ordered an Australian distributor to pay Nintendo over half a million dollars for selling the R4 mod chip, which allows users to circumvent technology protection measures in Nintendo's DS consoles. The distributor, RSJ IT Solutions, has been ordered to cease selling the chip through its gadgetgear.com.au site and any other sites it controls, as well as paying Nintendo $520,000 in damages."
Businesses

GameStop, Other Retailers Subpoenaed Over Credit Card Information Sharing 117

Posted by Soulskill from the you-can-trust-us dept.
New York State's Attorney General, Andrew Cuomo, has subpoenaed a number of online retailers, including GameStop, Barnes & Noble, Ticketmaster and Staples, over the way they pass information to marketing firms while processing transactions. MSNBC explains the scenario thus: "You're on the site of a well-known retailer and you make a purchase. As soon as you complete the transaction a pop-up window appears. It offers a discount on your next purchase. Click on the ad and you are automatically redirected to another company's site where you are signed up for a buying club, travel club or credit card protection service. The yearly cost is usually $100 to $145. Here's where things really get smarmy. Even though you did not give that second company any account information, they will bill the credit or debit card number you used to make the original purchase. You didn't have to provide your account number because the 'trusted' retailer gave it to them for a cut of the action." While there is no law preventing this sort of behavior, Cuomo hopes the investigation will pressure these companies to change their ways, or at least inform customers when their information might be shared.
Science

Antarctic's First Plane, Found In Ice 110

Posted by timothy from the ice-tractor-cometh dept.
Arvisp writes "In 1912 Australian explorer Douglas Mawson planned to fly over the southern pole. His lost plane has now been found. The plane – the first off the Vickers production line in Britain – was built in 1911, only eight years after the Wright brothers executed the first powered flight. For the past three years, a team of Australian explorers has been engaged in a fruitless search for the aircraft, last seen in 1975. Then on Friday, a carpenter with the team, Mark Farrell, struck gold: wandering along the icy shore near the team's camp, he noticed large fragments of metal sitting among the rocks, just a few inches beneath the water."
Games

EVE Online Battle Breaks Records (And Servers) 308

Posted by Soulskill from the blame-it-on-the-torrents dept.
captainktainer writes "In one of the largest tests of EVE Online's new player sovereignty system in the Dominion expansion pack, a fleet of ships attempting to retake a lost star system was effectively annihilated amidst controversy. Defenders IT Alliance, a coalition succeeding the infamous Band of Brothers alliance (whose disbanding was covered in a previous story), effectively annihilated the enemy fleet, destroying thousands of dollars' worth of in-game assets. A representative of the alliance claimed to have destroyed a minimum of four, possibly five or more of the game's most expensive and powerful ship class, known as Titans. Both official and unofficial forums are filled with debate about whether the one-sided battle was due to difference in player skill or the well-known network failures after the release of the expansion. One of the attackers, a member of the GoonSwarm alliance, claims that because of bad coding, 'Only 5% of [the attackers] loaded,' meaning that lag prevented the attackers from using their ships, even as the defenders were able to destroy those ships unopposed. Even members of the victorious IT Alliance expressed disappointment at the outcome of the battle. CCP, EVE Online's publisher, has recently acknowledged poor network performance, especially in the advertised 'large fleet battles' that Dominion was supposed to encourage, and has asked players to help them stress test their code on Tuesday. Despite the admitted network failure, leaders of the attacking force do not expect CCP to replace lost ships, claiming that it was their own fault for not accounting for server failures. The incident raises questions about CCP's ability to cope with the increased network use associated with their rapid growth in subscriptions."
The Almighty Buck

EA Flip-Flops On Battlefield: Heroes Pricing, Fans Angry 221

Posted by Soulskill from the put-your-money-where-your-gun-is dept.
An anonymous reader writes "Ben Kuchera from Ars Technica is reporting that EA/DICE has substantially changed the game model of Battlefield: Heroes, increasing the cost of weapons in Valor Points (the in-game currency that you earn by playing) to levels that even hardcore players cannot afford, and making them available in BattleFunds (the in-game currency that you buy with real money). Other consumables in the game, such as bandages to heal the players, suffered the same fate, turning the game into a subscription or pay-to-play model if players want to remain competitive. This goes against the creators' earlier stated objectives of not providing combat advantage to paying customers. Ben Cousins, from EA/DICE, argued, 'We also frankly wanted to make buying Battlefunds more appealing. We have wages to pay here in the Heroes team and in order to keep a team large enough to make new free content like maps and other game features we need to increase the amount of BF that people buy. Battlefield Heroes is a business at the end of the day and for a company like EA who recently laid off 16% of their workforce, we need to keep an eye on the accounts and make sure we are doing our bit for the company.' The official forums discussion thread is full of angry responses from upset users, who feel this change is a betrayal of the original stated objectives of the game."
Games

Games Workshop Goes After Fan Site 174

Posted by Soulskill from the don't-anger-your-base dept.
mark.leaman writes "BoingBoing has a recent post regarding Games Workshop's aggressive posturing against fan sites featuring derivative work of their game products. 'Game publisher and miniature manufacturer Games Workshop just sent a cease and desist letter to boardgamegeek.com, telling them to remove all fan-made players' aids. This includes scenarios, rules summaries, inventory manifests, scans to help replace worn pieces — many of these created for long out of print, well-loved games...' As a lifelong hobby gamer of table, board, card and miniature games, I view this as pure heresy. It made me reject the idea of buying any Games Workshop (read Warhammer) products for my son this Christmas. Their fate was sealed, in terms of my wallet, after I Googled their shenanigans. In 2007 they forbid Warhammer fan films, this year they shut down Vassal Modules, and a while back they went after retailers as well. What ever happened to fair use?"

Comment Do both (Score 1) 266

by fain0v (#29758059) Attached to: Should I Publish Or Patent?

As someone that actually went through this experience. Write your paper and your patent. Submit your paper, and submit a provisional patent. The patent is now pending. If your paper is popular, then you can make a decision to patent.

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