In islam, 100% of everything is about the religion. This leads to some very weird, distorted, and downright pathological thinking and actions. Although Iran is heavily muslim, most of those "muslims" are muslim in name only, very much the way a lot of christians in the USA are christians in name only.
The country seethes with hatred and discontent, mainly directed at the ruling clergy and not necessarily towards the USA and Isreal. Most Iranians couldn't give two shits about Isreal or the USA, they have too many problems of their own, like massive (>30%) unemployment, drug abuse, the mullahs pimping out Iranian women to the rest of the middle east, and so on and so on.