I don't do anything very advanced, but I am using Audacity running on Ubuntu Studio with a simple USB interface. This allows me to record, edit, playback audio and probably has a lot of other capabilities that I don't use and am not aware of. Audacity is plenty powerful for anything I'm likely to do at home.
Most music people I'm acquainted with are hooked on ProTools, which is prohibitively expensive as far as I'm concerned, but may have features and advantages that I wouldn't appreciate.