You're incorrect. You couldn't be more wrong.

In the case of old-style vaccines, the antigen is not attached to any cells. The only thing that the immune system attacks is the antigen.

For mRNA, you want the mRNA to stay local, since the mechanism has your own cells producing antigen, and those *cells* are attacked. Not an issue with muscle cells.

However,if the mRNA enters the bloodstream, it means that actual organ cells may be the target of the immune response, which in turn causes inflammation. The heart? Myocarditis, pericarditis. The ovaries? Sudden erratic periods. The brain? Brain fog.

This is why there were negative side effects. See: https://pmc.ncbi.nlm.nih.gov/a... - tl;dr is easily read in their conclusion:

"A wide distribution of vaccine mRNA in organs can lead to systemic adverse effects and, therefore, there would be a need in the future to develop lipid nanoparticles allowing targeted delivery of mRNA vaccines in specific cells..."

So no, you absolutely don't want a "generalized response" - at least, not from the underlying mRNA mechanism.

That's not how mRNA vaccines work, or at least, how they were advertised to work. You will not find any cite that indicates that they're supposed to enter the bloodstream. They were supposed to stay at the local site, and produce the antigen at the local site of injection.

See: https://www.cdc.gov/covid/vacc...

It clearly says:

"After vaccination, the mRNA will enter the muscle cells. Once inside, they use the cells' machinery to produce a harmless piece of what is called the spike protein."

Happy to see evidence to the contrary, but I doubt that you'll be able to produce it.

Didn't know that mRNA vax is not even cost effective for the most part.

I forgot one other issue:

* The mRNA has huge variation in how long it's in effect, in addition to how much antigen it produces. Not an issue with "old school" vaccines.

No more mRNA vax for me.

The covid mRNA vaccines are problematic for the following reasons:

* The mRNA does not stay localized (i.e., your arm muscle). It has been shown to travel all over the body. This may be partially related to how injects are administered. If you get an mRNA vax, ask for aspiration before injection to insure that they're not hitting a blood vessel.

* mRNA that arrives in the wrong place can cause significant issues for certain organs. This is likely the explanation for heart inflammation, erratic periods for women, brain fog, etc.

* There is no "off switch" - meaning that the amount of antigen that is produced varies tremendously for each individual. Too much antigen is not a good thing.

I will not touch an mRNA vax again unless and until these types of issues are addressed.

You are incorrect, at least for the "desktop" Linux version. It saves in ODF formats for the word processor, spreadsheet and presentation modes - just checked.

If AI was so great, this kind of influence purchasing wouldn't be required. Did Apple buy politicians in order to push the iPhone?

They're still SOLD, but they're not being produced. The prices for drives is spiking very quickly as remaining stock dries up.

I have two spares in the closet; they're about to become unobtanium.

I have tin ears and failing eyesight, but I can still tell the difference between streamed video and audio vs. what I've ripped from discs.

My modern desktop PC is in a modern case that has two drive bays (you can still buy them - Fractal Design Define R5), and is equipped with a flashed Blu-Ray drive that can handle UHD discs.

It's a bit of a hassle, but I can have whatever media I want where I want it, when I want it, the way I want it. Hunting down media is a fun hobby, too.

Anthropic was, at the least, making ephemeral copies of copyrighted works (i.e., the copy that existed in computer memory, possibly storage, temporarily).

I'm not sure (IANAL) that this concept has been applied to written works. For audio, however, the US mandates royalties in lieu of requiring a license - as getting a license would be impracticable.

I'm guessing that Anthropic is going get nailed for this aspect, as they likely would be required to acquire this type of license if they did what they did legitimately.

Who asked for this? How does it make the product better?

Pretty much any game that doesn't use Windows kernel-level anti-cheat will run pretty well. In some cases, a game might run faster on Linux/Proton. In come cases, a game might run a bit slower on Linux/Proton.

GrapheneOS is my daily driver. Some falsehoods that you're spreading:

Such as? I have the phone working with my banking applications, Android Auto compatibility is solid, and all of my apps run without issue. No more tap-to-pay, tho, but I just pull out my credit cards for that.

I've found that there's pretty much a 1:1 correspondence between being security conscious and having more technical acumen than a boomer-noob. I'd be amazed if you could find anyone in their potential audience (e.g., security concerned) that couldn't handle installing and configuring GOS on their phone.

I love GOS. I'm super grateful to the folks that have made it possible, and I was very happy to donate, too. They deserve it.

I'm guessing that this is a feature, not a bug (of the legal system).

Nothing wrong with a price hike for improvements. The problem is that the MTA had the money before the pandemic, but spent it wastefully.

NYC resident here. I think that the big issue is that the old mechanical signalling system has been an issue for decades, and that the MTA, even when it was flush, didn't prioritize it.

Hurricane Sandy took out several lines, and they claimed that they were going to upgrade to digital signalling as part of the restoration process. They didn't do it then.

The MTA, at one point, had an HR department that made up 25% of it's workforce (!). The history of waste, mismanagement, and misdirected resources is so damning that anything that they do should invite suspicion.