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Medicine

Submission + - First whole cancer genome sequenced (politigenomics.com)

dooling writes: "A paper detailing the sequencing of the first human cancer genome will be published in the 6 November 2008 issue of Nature. This is not only the first cancer genome published, it is the first female genome as well. You can read the paper's abstract, DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome, or the story in Science News. This issue of Nature also has articles on the sequencing of the first African and Asian genomes. The sequencing in all three articles was done using the Illumina Genome Analyzer, one of the massively parallel, next-generation genome sequencing platforms."
Patents

Submission + - The Rush to Patent the Atomic Bomb (npr.org)

dooling writes: "In case you were thinking of building your own atom bomb, you may want to weigh your intellectual property liability. It seems there are over 2000 patents covering the atom bomb. To avoid publishing the patents, a central tenant of the patent system, "the project made use of an obscure law whereby patent applications could be filed but no one would actually look at them or evaluate them. They would just be stamped secret and stored in a vault at the patent office." The irony here is that while all the patents were essentially stored in the same place at the patent office and written to be understandable by any engineer, the Manhattan Project worked diligently to compartmentalize knowledge, using code names for just about all aspects of the project and keeping tight security on all information. It seems the patents were filed to give the U.S. government an essential monopoly on the burgeoning nuclear industry and protect it against others who might patent similar technologies later."
Biotech

Corn Genome Sequenced 64

dooling writes "Later this week, the completion of the maize genome draft sequence will be announced. Maize has a large genome (slightly smaller than human) that is highly repetitive (about 80%). These facts made a whole-genome shotgun approach to sequencing infeasible. Therefore, a BAC-by-BAC approach was taken, similar to what was done for the Human Genome Project. Further work on the maize genome will focus on the parts of the genome that have genes, thereby avoiding the highly-repetitive regions of the genome (even though the maize genome is slightly smaller than human, it is thought to have about twice as many genes). You can read my take here."
Biotech

Submission + - Corn genome sequenced (wustl.edu)

dooling writes: "Later this week, the completion of the maize genome draft sequence will be announced. Maize has a large genome (slightly smaller than human) that is highly repetitive (about 80%). These facts made a whole-genome shotgun approach to sequencing infeasible. Therefore, a BAC-by-BAC approach was taken, similar to what was done for the Human Genome Project. Further work on the maize genome will focus on the parts of the genome that have genes, thereby avoiding the highly-repetitive regions of the genome (even though the maize genome is slightly smaller than human, it is thought to have about twice as many genes). You can read my take here."

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