I'm a grad student in the natural sciences. Some other friends of mine and I started Labmeeting.com because we are so eager to help change the way science gets published.
The current system of peer review is inefficient, arbitrary, and hidden from public view. We definitely need something new, but, as we said in our talk at BioBarCamp a while back, change needs to be gradual enough to preserve consensus.
That's why we're starting by just trying to make research tools that are useful to scientists in their everyday professional lives.