Comment here's what happened to me--specifically (Score 5, Informative) 199
i run 10.2.3, and have two main users, an admin and a normal user. i always log in a the unprivileged normal user and only use the admin for, uh, admin. duh. when files are downloaded, they go to ~/Desktop. i won't reveal my usernames for security reasons but they don't contain spaces. my admin user lives on the same disk as os x (/users/admin/), and my normal user lives on an external firewire disk (/volumes/disk/foouser/)
i download flat files from my bank to import into quicken. on every other browser i've used, clicking the appropriate link on the bank's page downloads a file "foo.qif".
safari comes out, i get it and use the default settings. i try downloading the file. safari shows me the contents of the flat file in the window. i go back to the previous page, option click on the link and choose "save link target as..." (i don't have the exact text, because safari is banned for reasons that will become obvious). the file downloads, i import it. fine. good.
i keep using my computer for a few days, using safari (but not option-click downloading anything). i read here about how this problem has happened. i logout from my normal user, log in as my admin user and delete /Applications/Safari.app, ~/Library/Safari/*, and everything else i can find with that name. (yes, i know i can do that from terminal, but i had other stuff to do in the gui.)
when i try to log back in as my normal user, i get the default desktop and dock. yikes! sure enough, my home dir /volumes/disk/user is empty except for . and ..
after a few minutes of panic & regret & resolutions to get a friggin cd burner for backups of those priceless photos of my kid, etc, i realize the disk usage hasn't changed. relief sets in and i realize the files aren't gone, they've just been misplaced. i log out and then log in as my admin user. i run disk utility and repair the external disk. it says the directory listing is incorrect and repairs it and then everything is magically good as new. i log in as my normal user and all my files are back.
i never had any printing problems.