mouse with the other hand (Score 1)

I'd like to second (or third, or fourth) this. I switched to mousing left-handed more than 10 years ago after a bout of tendonitis in my right wrist. I haven't had a recurrence. It took a few weeks to get comfortable, and the first couple of days were awkward. Persistence paid off, though. Now I can mouse either-handed. I didn't bother to change button locations.

I like the speed of selecting a region of text with my left hand while doing a command-key combo with my right.