The Asus PQ321 appears to be the same IGZO monitor as the Sharp PN-K321. I purchased the Sharp PN-K321 last week and found it had less dynamic range / contrast than the Dell 3011 it replaced, which meant that pictures and movies looked better on the Dell than on the Sharp despite the higher resolution of the Sharp. And it was very difficult to configure all my applications to display text at the desired size. Regardless of how I set it up, some fonts in some applications were either too small or too large. I returned it yesterday, and I wouldn't be surprised if many others meet the same disappointing fate. The only application I can think of is where you need resolution and are willing to give up contrast / dynamic range. Maybe it's good for displaying maps?