My Exp, with .NET and Game Dev Says Yes (Score 5, Informative)

I have been using .NET since September 2001. I wrote an open source 3D engine using C#. It makes use of BSP tree visibility culling, it uses WorldCraft as a level editor, it supports OpenGL and it did support NVIDIA's Cg until they changed their interface. When I released this engine open source back in February 2002 I stated clearly that I thought that .NET would be useful for game development.

ExoEngine - A C#, OpenGL .NET 3D Engine

PS. Some people notice that in the screen shots the engine is only getting about 10fps or less. This is because it was running without 3D hardware accelleration.