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Comment Actual article link and abstract (Score 1) 238

The antimicrobial action is hypothesized to be largely physical (disruption of the cell membrane leading to cell death). Barring some relatively significant mutations that greatly change the overall structure of the bacteria, a "resistance" would be relatively unlikely.

Here is the actual article link, since it's busted in the summary:


One-Step Photochemical Synthesis of Permanent, Nonleaching, Ultrathin Antimicrobial Coatings for Textiles and Plastics

Antimicrobial copolymers of hydrophobic N-alkyl and benzophenone containing polyethylenimines were synthesized from commercially available linear poly(2-ethyl-2-oxazoline), and covalently attached to surfaces of synthetic polymers, cotton, and modified silicon oxide using mild photo-cross-linking. Specifically, these polymers were applied to polypropylene, poly(vinyl chloride), polyethylene, cotton, and alkyl-coated oxide surfaces using solution casting or spray coating and then covalently cross-linked rendering permanent, nonleaching antimicrobial surfaces. The photochemical grafting of pendant benzophenones allows immobilization to any surface that contains a C–H bond. Incubating the modified materials with either Staphylococcus aureus or Escherichia coli demonstrated that the modified surfaces had substantial antimicrobial capacity against both Gram-positive and Gram-negative bacteria (>98% microbial death).

Comment Re:Bring on the hate (Score 1) 207

Fantastic. And it is great at that. It is when a company lacks much in the way of technical personnel decides that since it works so great for these smaller things it should be used for that Big Project as well, rather than going for the bigger initial investment of a proper database system. Or a user creates a little project for himself that Boss sees and decides everyone should be using because it worked so great for person X.

Any time it moves beyond the small projects it becomes hell to deal with from a technical standpoint. Which, unfortunately, I have extensive personal experience with.

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