There was a British TV show that put one on the roof of a tower block and demolished the tower, then threw it in the sea, and with some new spark plugs it was still working.
The show was Top Gear (Clarkson/Hammond/May era).
They started by buying a high-mileage second-hand Hi-Lux, drove it into walls and trees, then chained it to a slipway and let the tidal bore of the River Severn attack it - the chains broke, but they pulled it out of the sand when the tide went out and got it running "...with hammers and spanners and WD-40."
They then hit it with a wrecking ball and set it on fire. After the fire was out they drove it into the studio to much applause.
In a subsequent episode of the show, they took the same truck and put it on the top of the tower block, which was then blown up.
The truck still ran, was put on a plinth in the studio, and at one point Slash played their outro "Jessica" standing on it.
In another episode, two more Hi-Lux trucks - this time new - were driven to the magnetic North Pole.
Finally, they took one of those two and drove it up an active Icelandic volcano... which shortly after erupted and broke aeroplane travel for a while.
This is from memory, so I might have missed some details. One the other hand, I can't remember most of what I said at work today.
Anyway, I can't imagine doing the same with an F-150... at least, not successfully.