"You didn't use the right technique" is the first excuse used by researchers when their results don't hold up.
In Bio science this reproducibility problem is, at heart, a problem with having an experimental system that is under control, well defined and "stable".
There are plenty of very precise measurements made that are not accurate because there is something about the experiment that is not under control.
In biology, even if you do your best to account for statistical variation, it can often be the case that your results are bunk because there are things going on beyond your ken.
This is a real problem, people are now taking it seriously. It has impacted on my life in science on numerous occasions. I don't start something based on others' work unless I've tested the underlying rationale.