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Comment True for most people, but not these (Score 1) 298

Top-level researchers have generally already moved internationally across the globe multiple times during their career - one or two post-docs, junior faculty, assistant professor, full professor - these routinely require you to move whereever in the world your research profile is valued. These people are not scared by moving once more. And the language of research groups is English anyway, everywhere.

Comment And other countries are preparing to welcome these (Score 1) 298

The EU is already formulating a program to welcome exiled top scientists with open arms and funding. China has had a similar program for some years already. If the brain drain really gets traction, this will harm the scientific competitiveness of the US for decades (but the university and college football teams will remain awesome and continue to make good television).

Comment This will soon end (Score 1) 104

A surprisingly large fraction of the US Nobel Price winners are immigrants born and initially educated in other nations, not US-schooled native citizens. They were drawn to the top universities to start their scientific career. During their one, two or three decades in the labs toiling at their research projects they became US citizens before they received the Price.

Due to the current political climate, the top talents have begun to leave the US, not move into it. The EU is preparing a program to lure top US researchers to Europe, and so has China for quite a while.

Comment Semaglutide is a peptide (with some decorations) (Score 1) 295

The core structure is made by a genetically modified yeast, which needs to be grown under very controlled conditions in a sterile bioreactor. Good luck with that in your home lab.

The first experimental samples were actually made synthetically - by a sequence of close to 100 distinct chemical reactions. Good luck again, and this approach will be orders of magnitude more expensive than just buying the product.

Comment That is something different (Score 1) 295

Magistral preparation means a pharmacist prepares an ointment, eye drops etc. by compounding raw pharmaceutical compounds with solvents, ointment bases, etc.. This is pure galenics. Pharmacists do NOT chemically synthesize pharmaceutical ingredients. Extracting ingredients from natural products to obtain some substance is maybe a borderline case.

Comment Completely insane (Score 1) 295

Running a reaction is one thing (if you are lucky enough not to poison yourself - their promoted set-up does not even include a standard hood). But distributing stuff with no proper purification and, even worse, zero analytics is plainly criminal.

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