Even though genetic drift isn't as big of a factor anymore, there's still the matter of a dramatically altered environment - not so much in a, "global warming," sense as a, "humans have lately been adapting to a completely different definition of fitness than the one that got us to where we are now," sense.
The main thing that comes to mind is sexual selection. If nothing else, the centuries will tend to look kindly on the families that are best at attracting mates, keeping them, and seeing to it that their kids are able to do the same.
What's more, while we don't have much in the way of natural predators anymore, we still occasionally get someone with a mutation that gives them an edge, and in that case the genes tend to spread like wildfire.
As a semi-relevant example: It used to be that most people couldn't drink cow's milk without puking. Soon after it was discovered, though, it became apparent that those who could stomach this new food had an almost flukish advantage, and so over time we've gotten to the point where most people have inherited the ability from some ancient milk-drinker or another.
In summary, it will be a long time before humanity technically develops into a different species, but along the way we'll probably become super hot and learn to drink milk.
