I have been using Dasher for the vast majority of my typing needs for the past year. I was diagnosed with Lou Gehrig's disease (ALS) about two years ago and have slowly lost the use of my left hand and arm during those two years. Dasher is commonly recommended to paraplegic and quadriplegic patients. I know several ALS patients who use it with eyegaze or headmouse setups and love it. It should be usable on any *NIX system that supports GNOME. There are also Windows binaries available.
Another possibility that can be used is an onscreen keyboard with dwell clicking for the mouse and word prediction capability in the keyboard software. I know that both xvkbd and the GNOME onscreen keyboard (GOK) both support word prediction. There are also a couple of projects that have adapted the Dasher word prediction engine into an interface like a telephone keypad that could also be used with dwell-clicking to provide a decent interface. Seems to me one of those projects was called Tapir and the other one was called dKeys.
If anybody becomes interested in this kind of stuff and decides to take on a role in contributing to some of these accessible software projects, you will have the appreciation of hundreds of thousands of disabled users worldwide. Not a bad reward for a little bit of work.