I know one person's already done this, but I'm gonna jump in too, because why not!
1. Self-Driving Cars will destroy one of the few low-skill-high-paying career tracks left. On top of the unemployment created by this, self-driving cars will reduce the need for car ownership, and in turn centralizes the routine upkeep vehicles require. From an environmental perspective this is wonderful, but imagine every single gas station, car parts manufacturer and retailer, and auto-service station going out of business. Consider the ramifications of the entire secondary industry tied to the automobile collapsing entirely.
2. Clean Energy will require a complete restructuring of the electrical grid. While homes will be more self-sufficient, our current grids are not designed for the decentralized nature that solar and wind production introduce. Existing energy (read: oil and gas) companies will pivot- they already are- to maintain their grip on energy production. They have the resources to do so.
3. Virtual and Augmented Reality won't make us any less social than before, despite naysayers, but they'll separate the idea of "experience" from "real experience". This in turn will price live attendance of events out of the range of most people. Sure, I could afford to get "front-row seats" at a concert now, but that experience will be shared between thousands of people, and leads to the homogenization and commodification of experience for a significant percentage of the population. An experience inequality, if you will (beyond what exists today).
4. Drones and Flying Cars are a security nightmare. Flying cars- if they ever get off the ground- will be a safety hazard that will require a complete redefinition of current air control laws. Drones are already proving their potential to cause harm in wars being fought in Syria and Iraq, and it's only a matter of time before we see more drone-based terrorism elsewhere in the world. Beyond that, privacy and security concerns have already been raised today, and will only magnify as the technology gets even cheaper and more robust.
5. Artificial Intelligence will wipe out a significant majority of white-collar jobs, full stop. Algorithms that are unconsciously biased will create significant hardships for large percentages of local populations, and the system will now be even more systemic, because hey, "it's a computer". And while I don't buy into it at all, let's throw in the Singularity for good measure.
6. Pocket Supercomputers for Everyone means pocket surveillance devices for everyone. As the economics of Software as a Service plays out, we'll probably find those pocket supercomputers turning into pocket ball-and-chains. Vendor lock-in. And malware is only going to get worse on the very devices that know more about us than any other.
7. Cryptocurrencies and Blockchains will mean a sustained, untraceable black-market, despite the eventual phasing out of physical currency. Blockchains create paper trails that provide proof-of-purchase, and can and will be use as a means to enforce DRM.
8. High-Quality Online Education is, no matter what its proponents say, a fancy way of saying "books", and we've had books for a while now. Online education does not replace proper pedagogy, but it will syphon enough dollars away to further hurt actual education providers. And who says knowledge should be free when your courses are proprietary?
9. Better Food through Science means better food control through patents and litigation.
10. Computerized Medicine means another attack vector for hackers (gonna out and out give props to HeckRuler for that one). In case we weren't done wiping out white collar jobs, let's get rid of doctors and medical researchers too, while we're at it. And while breakthroughs will be disseminated quicker than they are now, that also means that incorrect results mistaken as breakthroughs will too.
11. A New Space Age means the continued privatization of resources, as companies claim technologies and land/mineral rights for themselves. Y'all ought to read The Space Merchants.
So there's a nice long list of negativity for you. For what it's worth, I'm very much being as negative as possible here. Several of the technologies (particularly #1, 2, 9, and 10) above are going to cause serious problems along the lines I listed/guessed at, but those problems should be solvable one way or another, and the benefits are absolutely worth it. So hurrah for a complex world where costs and benefits intermingle in ways that are both thrilling and horrifying!