It is religion if we say that science produces knowledge that is reality.
As I see it, science is a technology that produces higher qualities of usable knowledge. Religion does not produce knowledge. It is apples and oranges when arguing one against the other.
My other argument is that if science is BS, as Socrates may say, it is very effective knowledge. Do we care if it is reality so long as my plane can create lift or that I can power my computer with electricity? No, so long as the algorithms that create the effect are always valid. I think this is a more humble approach that science asks us to consider so that it can continue creating new knowledge.