I recently thought about the configuration thing and how little I customize my boxes anymore. I used to run all the interface tweaks, hacked themes, bunches of customization addons for shortcuts and macros, etc etc. Now about all I do is stick my taskbar on the left (on widescreens), switch it to show labels, and maybe turn the colors to a dark theme. I just don't have the patience or motivation to mess with the level of customization I used to.
I do still play with Gentoo on several boxes, including a couple laptops, but it's definitely gotten to be more and more hassle.