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Comment Re: Oh well (Score 2) 104

One of the companies that makes the most by selling HIV treatments (Gilead) made their biggest profits and biggest stock market gains by curing Hepatitis C.

Big pharma companies would love to invent more cures: who wouldn't want to own the entire market for a disease instead of having to compete with other treatments? But cures are typically much more difficult to develop, and in many cases will have to be tailored to individual patients. We're really only beginning to have the level of sophistication necessary to do this.

Comment Re:Personally willing to pay for a subscription. (Score 1) 134

EPreviously users were baited to click on a search result using an unclear headline and a misleading snippet, then had to accept cookies,

Well, no. Previously when people wanted to "get my news" they didn't use search, they went to news sites and read the news.

Why do publishers act surprised, that people prefer the clean experience over their sites that use the content mostly to get users to click on ads? If they can't manage to provide a better experience, their click-through rate will diminish. And blocking the search engines from accessing their content will only make it worse.

The NYTimes has been gaining subscribers every year for a decade now, and generates most of its revenues from subscriptions, not ads. And I just tried turning off my ad blocker before visiting: the site works fine either way, and isn't festooned with ads either way. NYT is certainly an exception these days, but it does show that someone is still managing to do actual journalism and get paid for it.

Comment Personally willing to pay for a subscription. (Score 1) 134

I tend to like to get my news on ground.news nowadays, and often read the linked article..

An AI summary of the story, with the option of going to the sources used. The left/right bias scores for the sources are nifty, but ultimately Ground is doing the same thing that Google is doing, and thus causing the same problems.

Comment Re:Death of Clickbait Journalism is A Good Thing (Score 2) 134

While Bezos is cranking up the process of turning the Post into a zombified corpse, currently it is still stands as one of the largest employers of actual, full time, fully qualified journalists who are paid to take the time to go talk to real live people, dig through spreadsheets and corporate records, check their sources against other sources, and do, you know, real journalism. Pulitzers they won in 2024;

National Reporting: Staff of The Washington Post

For its sobering examination of the AR-15 semi-automatic rifle, which forced readers to reckon with the horrors wrought by the weapon often used for mass shootings in America.

Commentary

Vladimir Kara-Murza, contributor, The Washington Post

For passionate columns written under great personal risk from his prison cell, warning of the consequences of dissent in Vladimir Putin’s Russia and insisting on a democratic future for his country.

Editorial Writing

David E. Hoffman of The Washington Post

For a compelling and well-researched series on new technologies and the tactics authoritarian regimes use to repress dissent in the digital age, and how they can be fought.

Between Google and Bezos I think they'll be clickbait soon enough though. Which really sucks for this country - we're running out of legitimate news sources.

Comment Re:Pills Won't Stop Your Sin (Score 1) 181

Let's add some numbers to that math:

The overlapping physiological changes that occur with weight loss help explain the near-ubiquitous weight loss time course: early rapid weight loss that stalls after several months, followed by progressive weight regain32. Different interventions result in varying degrees of weight loss and regain, but the overall time courses are similar. As people progressively lose more and more weight, they fight an increasing battle against the biological responses that oppose further weight loss.

Appetite changes likely play a more important role than slowing metabolism in explaining the weight loss plateau since the feedback circuit controlling long-term calorie intake has greater overall strength than the feedback circuit controlling calorie expenditure. Specifically, it has been estimated that for each kilogram of lost weight, calorie expenditure decreases by about 20–30 kcal/d whereas appetite increases by about 100 kcal/d above the baseline level prior to weight loss31. Despite these predictable physiologic phenomena, the typical response of the patient is to blame themselves as lazy or lacking in willpower, sentiments that are often reinforced by healthcare providers, as in the example of Robert, above.

https://pmc.ncbi.nlm.nih.gov/a...

Comment Re:Sounds cheap and easy (Score 2) 85

Except someone would have to pay for that. Meanwhile, the Federal government just eliminated the laws requiring municipalities to monitor some of the forever chemicals and delayed implementation for six years for others.

So municipalities won't be measuring for this, won't be forced to fix it if they find something, and won't be getting any money federal money to fix it if they want to.

Comment Clinical trial results (Score 1) 48

The same way you know about the safety and efficacy of other drugs:

https://loyal.com/posts/our-lo...

If they don't register and make public the details of the trial well before the results are announced, if they don't replicate it in a second trial, if their study size, duration, or retroactively chosen endpoints are cheesy, well, so much for that. The $100M question though is will they find a way to sell it off label to humans?

Comment Re:Federal conviction upheld on appeal, so ... (Score 1) 101

Depends on the investors. If she conned George Soros: pardon. But instead she conned:

- Larry Ellison, who participated in Trump's 2020 attempted election theft

- Fortress Group, which loaned money to Trump, forgave the loans, and received favors in return

- Rupert Murdoch

No pardon for her.

Comment Re:Arrest rates (Score 1) 26

My point is that the places doing more retracting are likely the ones performing more rigorous checks,

Or those places are not doing rigorous checks at all. They are just responding after international teams of volunteers using digital tools to spot plagiarism, photoshopped data, and other signs of fraudulent research make the problems public.

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