I buy all of my games (Which are all PC games). I use the original media to install them, then I store the disks in a safe place where they will not get dirty or scratched.
I fire up a game and get a message : "Please insert disk one of <Insert game name here> into your CD-ROM/DVD-ROM drive." People around me can hear my teeth grinding every single time!
Let's see... If I want to play many different games, I have to keep all the disks handy. Every single time I switch from a game to another, I have to switch disk. Furthermore, I have a lot of data stored on DVD, so every time I want to access it I find some game DVD in my drive.
Do you even wonder why I use No-CD/No-DVD patches? I see it like patching a problem or bug with the game.