Comment A few options (Score 1) 550
First, you will have to accept that if she simply doesn't like video games, you shouldn't try to force her into playing with you. My wife generally doesn't like video games but she's happy to let me play while she does her own thing most nights.
However, my wife does enjoy playing a few games with me. One is You Don't Know Jack, a humorous trivia game. The most recent version is available on consoles and Steam and has plenty of content. She enjoys playing New Super Mario Bros Wii in co-op mode as well.
We recently got a Kinect and now my wife wants to play that more than I do. The game that comes with it, Kinect Adventures, is fun, and she also enjoys an exercise "game" (Your Shape I think). We have Dance Central 3 but both of us are horrible dancers so I'm not sure how much use it will get (I also can't stand pretty much any song in the setlist). Anyway, the point is that these games are different enough from your standard controller-based ones that people who normally don't like video games may be more willing to play them.
Another option is board games. There are a lot of great European-style board games out there that can be played with 2 players. Some of them are co-operative as well which can help avoid your wife being turned off by the competition. Carcassone is a great competitive game for 2 (or more) players, and if she likes that, there's a downloadable console version that seems to be very faithful to the original game (as well as being a lot cheaper). Which would be another way to help her accept video games a bit more--video game versions of board games she already enjoys.