Scientists in Portugal and Germany report of research that suggest a new therapy to control the spread of tumour cells to new tissues, a process known as metastasis and that is associated with high risk of a fatal outcome. The research describes how the chaotic, increased motility of some tumour cells, known to be crucial for metastases, can be linked to the aberrant activation of a molecule called epidermal growth factor receptor (EGFR). It also shows how inhibition of this activation reverts high motile cells into a normal benign pattern of motility. The research suggests that EGFR inhibitors, which are readily available in the market, could be a potential new therapy in the control of metastases in some type tumours.