Comment Fatigue will be a problem (Score 1) 65
When I started working for an imaging lab in a midwest medical institution in 1984, we were exploring the utility of a vibrating mirror display, which provided a real 3D image (you could move your head to see behind things). Part of my work involved support software for point, line and plane cursors to segment and refine the image. The cursors were driven by a freespace mouse (we called it a "bat") which you held in one hand. Given poor response times, it was difficult to control the device for more than a few minutes with your hand in the air, especially as you waited for the cursor to catch up with your movement. Modern technology could eliminate the slow response, but keeping a hand motionless in the air for extended periods can be a problem.