When I was growing up refrigerators and cars used Refrigerant 12, also known as Freon or CFC-12. It was non-flammable, efficient, nominally non-poisonous and safe, and easily made. It was even a critical ingredient in asthma inhalers. It had one problem, however. It was a Super Pollutant that punched tiny holes into the ozone layer. (It was only later, after the ozone problem was solved by banning CFCs, did global warming numbers begin to pop up next to replacement refrigerants like HFC-134a as well as historical references to R-12. Nobody cared about GWP before, and I should point out that GWP is about global warming potential, which in reality is likely far less.) Next, the new Super Pollutant was HCFC-22, which did far less ozone damage but still had to be banned... in favor of HFC-410a with a larger GWP! Now the new Super Pollutants are HFC-134a and HFC-410a, etc
My point is simple: every time a problem is addressed, someone will lose their sh*t with the replacement chemical eventually, forcing everyone to make yet another costly change. I am not against progress, but this doesn't have to be done with a heavy-handed phase out. It could be done simply by making new devices with new refrigerants, while not restricting production of current gasses.
Mark my words: when HFCs are no longer available as refrigerants, someone will come for HFO refrigerants, like R-1234yf, even though the GWP is less than that of carbon dioxide, because they will find something wrong with it. There is also money to be made in forcing an industry to adopt new tools, equipment, chemicals, and processes. And for those who say this is based on good earth science, I will remind you of the countless predictions about sea level and global temperature that have never come to fruition.