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Submission + - Flight Data Recorders, decades out of date (ieee.org)

Tisha_AH writes: "For the past fifty years the technology behind aircraft flight data recorders has remained stagnant. Some of the advances of cloud computing, mesh radio networks, real-time position reporting and satellite communications are held back by a combination of aircraft manufacturers, pilots unions and the slow gears of government bureaucracy. Many recent aircraft loss incidents remain unexplained with black boxes lost on the bottom of the Atlantic Ocean, buried under the wreckage of the World Trade Centers or with critical information suppressed by government secrecy or aircraft manufacturers.

http://spectrum.ieee.org/aerospace/aviation/beyond-the-black-box/0

Many recorders still rely upon tape recorders for voice and data that only record a very small sampling of aircraft dynamics, flight and engine systems or crew behaviors. For many aircraft the recorders can only log a hour or two of data before overwriting the tape. All recording stops if the main electrical system fails and there is the ever present circuit breaker in the cockpit that can shut the system down.

Technologically simple solutions like battery backup, continual telemetry feeds by satellite and hundreds of I/O points, monitoring many systems should be within easy reach. An example of an extensive (but still primitive) recording system was during the loss of the NASA Columbia space shuttle. This vessel was equipped with a much larger assortment of monitoring points as it was used as a test-bed during shuttle development. Without the extensive forensic analysis of the telemetry data it would have been nearly impossible to reconstruct the accident in such detail. http://spaceflightnow.com/columbia/report/030826crew/

Pilots unions have objected to the collection and sharing of detailed accident data, citing privacy concerns of the flight crew. Accidents may be due to human errror, process problems or design flaws. Unless we can fully evaluate all factors involved in transportation accidents (aircraft, maritime, rail, transit) it will be difficult to improve the safety record. Recommendations by the NTSB to the FAA have gone unheeded for many years. http://www.policyarchive.org/handle/10207/bitstreams/3687.pdf

With all of the technological advancements that we work with in the IT field what sort of best practices could be brought forward in transit safety?"

Businesses

CTRC Orders Big ISPs To Provide Matching Speeds For Resellers 91

Meshach writes "In Canada there has been a regulatory decision rendered by the CRTC ordering ISPs to provide the same speed to resellers as they do for their own customers. 'Smaller internet providers such as Teksavvy and Execulink had argued that without requirements to offer matching speeds, the big companies would put them out of business. Bell and Telus are selling internet connections of up to 25 and 15 megabits per second respectively over newer fibre-based networks, but smaller providers can typically offer speeds of no more than five megabits per second over older copper-based infrastructure. After holding a public hearing earlier this year, the CRTC now says it will allow phone companies to charge smaller providers an extra 10-per-cent mark-up to use their newer infrastructure in order to recoup the costs of their investments. The regulator also said it would require cable companies to modify their existing internet access services to make it easier for smaller, "alternative" providers to connect to them.'"
AMD

Submission + - It's official: AMD will retire the ATI brand (techreport.com)

J. Dzhugashvili writes: A little over four years have passed since AMD purchased ATI. In May of last year, AMD took the remains of the Canadian graphics company and melded them into a monolithic products group, which combined processors, graphics, and platforms. Now, AMD is about to take the next step: kill the ATI brand altogether. The company has officially announced the move, saying it plans to label its next generation of graphics cards 'AMD Radeon' and 'AMD FirePro,' with new logos to match. The move has a lot to do with the incoming arrival of products like Ontario and Llano, which will combine AMD processing and graphics in single slabs of silicon.
Earth

Submission + - Hydrogen fire and explosion renewable fuel station (13wham.com)

RossR writes: There was a Hydrogen fire and explosion renewable fuel station used by government vehicles. The nearby freeway and airport was closed resulting in diverted flights. This may the first major incident at a Hydrogen vehicle refueling station. GM has their major fuel cell development center nearby in the town of Honeoye Falls. The fire occurred when the 18-wheeler tractor truck was transferring Hydrogen to the station. The airport press conference reported that airport firefighters responded first and initially waited on the scene deciding how to respond. No news yet if the hard to see flames of Hydrogen combustion contributed to this delay. The fueling station is also adjacent to a NY State Troopers station and a firefighting training facility is a few blocks away. It will be interesting to see how this incident affects the future of Hydrogen cars.

So far this is has been only covered by local news:
http://www.13wham.com/news/local/story/Hydrogen-Explosion-Near-Rochester-Airport/xu3d9NK_cE2sbQy8qByf3Q.cspx

Police/FD Radio transcript:
http://www.radioreference.com/apps/audio/?ctid=1852

HAZMAT
08/26/10 13:08(ROCHESTER — 154.130) UPDATE:; TOTAL FAILURE OF A HYDROGEN TANK AT FUEL FARM. AIRPORT & I-390 BOTH DIRECTIONS CLOSED TFN. [NYK015]

HAZMAT
08/26/10 12:59(ROCHESTER — 154.130) UPDATE: RFD REPORTING FLAMES FROM A HYDROGEN TANK, COMMAND/INCIDENT COMMANDER REQUEST 5 INCH LINES INTO THE SCENE. [NYK015]

HAZMAT
08/26/10 12:55(ROCHESTER — 154.130) FIRE DEPARTMENT ON SCENE WITH A RUPTURERD HYDROGEN TANK AT THE AIRPORT FUEL FARM, FULL HAZMAT REQUESTED. [NYK015]

Comment Re:Misleading title (Score 1) 148

i think they are called "pilots" actually.

Actually, as a tongue in cheek thing, most pilots refer to other pilots as "drivers", as in "What equipment do you drive?"

(Equipment is an informal industry term for the type of aircraft. (Type is a formal industry term for the make and model of aircraft (Type is based on certificate, not marketing make & model. (I always get lost with nested brackets.))))

Comment Re:I don't blame them. I ditched the industry too. (Score 3, Interesting) 137

(I'd rather reply to this than spend my mod points.)

Yes, long-haul commercial pilots are well paid. The problem is getting one of those jobs. There's a huge over supply of pilots. I'm a pilot myself and I'm very glad I never tried to make a living out of it.

Once you are in the company, your position is based not on skill or ability or how hard you work. It's based entirely on how senior you are. That in turn decides how much you get paid. Typically you start off in the right seat of turbo-prop commuters getting paid almost nothing. In fact, "self-sponsored" positions aren't unheard of. If you manage to stay with one company long enough that you're no longer part of the "last in, first out" cuts, then your job is safe but your salary still isn't that great. It's only when you start edging towards retirement that the pay starts to reflect the amount of training and seat-time you've put in while earning peanuts. If your company goes bankrupt or you switch companies, you may find yourself at the bottom again.

Image

Justice Department Seeks Ebonics Experts 487

In addition to helping decipher their Lil Wayne albums, the Justice Department is seeking Ebonics experts to help monitor, translate and transcribe wire tapped conversations. The DEA wants to fill nine full time positions. From the article: "A maximum of nine Ebonics experts will work with the Drug Enforcement Administration’s Atlanta field division, where the linguists, after obtaining a 'DEA Sensitive' security clearance, will help investigators decipher the results of 'telephonic monitoring of court ordered nonconsensual intercepts, consensual listening devices, and other media.'”

Comment Re:Cheap microscope (Score 2, Interesting) 216

I like the way you think. I like the idea of going after the protein capsid in a catalytic manner. The problem is prions are very odd and rare things in themselves.

Technically speaking, a prion protein has to have a diseased-conformation with a lower thermodynamic energy minima than the the healthy version, otherwise it would require energy input, and thus be non-catalytic. Since most proteins are already folded to minimum energy, it's unlikely you can find a lower energy conformation that has catalytic activity for a HIV protein such as GP120 (or any other protein for that matter).

BTW, some researchers don't believe prions are really prions. They believe a small amount of genetic material may lay hidden. These researchers aren't crackpots and demonstrating the presence of DNA/RNA inside would explain a lot of weird stuff that can't be explained when it comes to prions.

Comment Re:So which drug company is going to buy the (Score 1) 216

(No worries about knowledge level. We're all here to learn, and I'm probably wrong about somethings.)

So, HIV goes latent, so there is effectively no virus. There is nothing for the drug to kill. When HIV goes back into the lytic cycle, you have to have the drug there to kill the virus, but you don't know when HIV goes back to lytic; it can be 2 weeks or 2 decades. You would have to keep the patient on the drug during this whole time or at least keep monitoring the patient and giving them the drug whenever it flares up.

(That's the simplified version. The more complicated version involves HIV never really going latent in the lymphoid organs, slowly infecting more and more CD4 cells, leading to AIDS. It could be that if this drug can get into the lymphoid tissues, you can reduce the viral load inside to make them long-term non-progressors, but that's more complicated.)

Comment Re:So which drug company is going to buy the (Score 1) 216

The RNA from HIV is retro-transcribed into DNA which is integrated into the host cell genome. It can become latent where it does not actively replicate virus. That's why HIV patients can live so long. Something then later triggers the lytic phase where the viral replication resumes, eventually leading to AIDS.

An agent that kills HIV will remove HIV from your system, but the latent virus DNA inside cells remain undetected and cannot be removed.

Comment Re:So which drug company is going to buy the (Score 3, Informative) 216

Even if you can kill the HIV virus, you still wouldn't have a cure.

HIV is a retrovirus. It becomes part of the infected cell's genome. Any agent that kills the virus can suppress symptoms/disease but not cure people who are already infected.

P.S. Please take off your tin-foil hat. The glare is quite annoying.

Comment Re:$225,000 (Score 3, Informative) 216

The 400x part is usually meaningless. It's just 40x objective and a 10x eye piece. What actually matters is the resolution.

Resolution can be improved by things like deconvolution as used in TFS, but that's still relatively low. You can easily start flirting with 7 digit figures when you use confocal microscopy and variations of laser excitation. See: http://en.wikipedia.org/wiki/Confocal_microscopy

Comment Cheap microscope (Score 4, Insightful) 216

As a biologist, I have no idea why they're making such a big deal of it being a $225,000 deconvolution microscope. It's cheap compared with what most institutions have. Besides which is the fact that the microscope used isn't interesting. Any high(ish) resolution fluorescent microscope would have given you the same data. The interesting part is this TRIM5a. Let's see what happens with recombinant TRIM5a in animal studies.

Science

Submission + - Researchers zero in on protein that destroys HIV (physorg.com)

Julie188 writes: Using a $225,000 microscope, researchers have identified the key components of a protein called TRIM5a that destroys HIV in rhesus monkeys. The finding could lead to new TRIM5a-based treatments that would knock out HIV in humans, said senior researcher Edward M. Campbell, PhD, of Loyola University Health System.

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