1. For Profit Health Care.
Can you make a profit if people don't get sick? Or, if they are already sick and you find a cure where will you profit from next?
2. Mental/Emotional Health.
Watch enough TV(or internet) news, trigger your fear/anger response, watch more TV (or internet) news, add to pre-existing fear/anger response (repeat until ill)
3. Poor Parenting
All babies are born a blank canvas with autonomic systems for basic function. Our jobs as parents is to program the correct pathways before neural pruning establishes the "defaults" which become our firmware. The basic emotional processing that is built in to everyone builds with an almost "Crazy Glue" stickiness which gives emotional weight to our memories. Bug Filled Firmware -> Bug Filled Person
4 Poor/Failing Society
All great empires in human history have failed. Once the failure is irreversible the values and morals are the first thing to go.
These are my top 4, if I continued the list... Environmental Pollution, and Splitting some of the above into more detailed points would be easy.
Sunny and Warm here by the Beach