Always better to wait (Score 1)

It's always better to wait until you have found another job before you quit. In the situation you describe a prospective employer could take your lack of cooperation in working with Microsoft tools as inflexibility. That will make it harder for you to find another job. In the current job market there will always be someone else willing to do what you are refusing to do. All you are doing is giving them a chance to hire someone else who's willing to do the job. You may prefer not to work with Microsoft tools, but in the end it's just that, a tool. There are much worse things that you could be asked to do. A few years ago I quit a job that I had only had for a short time. The primary reason being that I ended up hating the job and the people I worked with weren't much better. The employer in question was not completely up front about what was required in the position. This of course was my fault for not asking more questions before I accepted. Also on my first day at this job there was a news article talking about the possible demise of the product produced by this same department (not a good sign). Sure enough work on that product was halted about 3 months after I quit. This means that if I had just put up with it for a few months I would have had at least a year's worth of severance pay or a shot at working in another department where I might actually have been happy. Instead what I got was a year and half of being unemployed and then just landing a part time job (where I'm at now). Although, I don't regret leaving a job that I hated I do regret not finding another job first.