10 years ago, business were just embracing the Internet. A lot of companies were letting go of Novell Netware and placing baby steps out there on the net.
In those last ten years, a vast amount of services we used have been forgotten. Does anyone still use MySpace or Lycos for instance. In a couple of years the names like Flickr, Facebook, Twitter and the like will be replaced by something more social and closer to the needs of the people.
In business, the idea of a computer on every desk will become a computer in every hand as the needs of computers become that of a personal experience. I can see a merge between the home and business more likely to happen where you have one device for your company that works equally well at home. Less requirements for being in a physical building give way to home based working or virtual office cubicles.
I can see the power being moved back to the client-server model which served us well until the advent of the PC. Now with the PC market beginning to wane, the client-server will become more the tiny box you plug in that gives you your wireless signal and virtual desktop environment as well as the connection to your ISP.
There will still be a need for someone to set these boxes up, so the sysadmin/network engineer becomes a similar role to the technical support engineer who drives to a location to repair a computer.
Perhaps there will be a direct connection with the brain in 10 years time, so you think what you want to do and the computer relays the images and audio as synaptic responses to and from the brain directly. That way there would be no need for a tablet or gestures of the hands or fingers. The potential for zombies would be more of a problem though!