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Comment Re:Uh, what? (Score 1) 193

Agreed. There are 2 major issues with neurogeneration. 1. Getting the damaged CNS motor Neurons to regenerate instead of dying. If a CNS neuron perceives through various cell signals that it has sustained enough damage, it will undergo Apoptosis(cell suicide). The degree of damamge and the type of damage(crushing vs transection)will make a difference. So the PEG might have some effect here if it indeed has one. 2. Getting the damaged CNS Motor Neurons to connect back to the right place! There is a huge amount of distance the axon will have cover as it regenerates. There isn't a long range cell signaling system for the adult human neuron. chances are, the more distance you have to cover, the less likely the axon will get back to where it was. Even in short distances regenerations, loss of detexerity is possible. BTW, when they talk about spinal regeneration, I think most of them are talking about axonal regeneration, if the cell body is toast there isn't much you can do.

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