http://www.bestpractical.com/rt/ (Score 3, Interesting)

This software has completely changed my life. I use it as a TODO list, I use to to manage developers, I use it to manage myself, and I'm now using it to manage the process of renovating my house (will eventually require my contractor to use it). I will never go back to the days of using a TODO list that's bound to a particular phone, handheld, laptop, or desktop.