Comment Only if the content is visible first (Score 1) 214
Unfortunately, the content matters little if the color scheme is so dreadful that the user has to highlight the text or open the source HTML to read said content.
... you think I'm joking, but making your teeny-tiny-point font match your background color seems to be popular in certain web circles. I have found this correlates highly with the "2 inch by 2 inch iframe" and "I'm 1337 with my warez copy of Dreamweaver" school of web design.
My point is that you're assuming a minimum level of usability to the color scheme to begin with, and I think that that's a dangerous assumption.