Comment Cousin of Fugu already used for gene finding! (Score 2) 138
The idea that a compact genome could be used to look for genes (or at least exons) in the human genome has already been put into practice. If you go to http://kicy.genoscope.cns.fr/cgi-bin/exofish_kicy. cgi you will get a short introduction on the topic as well as have access to the interface allowing you to look for exons in a sequence that you input.
EXOFISH (Exon Finding by Sequence Homology) uses DNA from another fish which is a cousin of Fugu (Tetraodon nigroviridis) in order to find highly conserved regions between it and human sequences. A method was developed to find these evolutionary conserved regions (ecores) efficiently as it is believed that they represent exons. More info here.
EXOFISH (Exon Finding by Sequence Homology) uses DNA from another fish which is a cousin of Fugu (Tetraodon nigroviridis) in order to find highly conserved regions between it and human sequences. A method was developed to find these evolutionary conserved regions (ecores) efficiently as it is believed that they represent exons. More info here.
