Small-office Windows based backup software?

Billhead writes: My boss purchased a Quantum SDLT220 tape backup drive for our few computers in the office, I was have been put in charge of maintaining the backups. The only prior backup experience I have is with my home networks using Python scripts. We don't have any special needs, just encryption and scheduling. Our original backup software isn't compatible with the SDLT220, and other backup software we have tried have been horrible(unable to decrypt backups, memory leaks, unstable network backups). What does the Slashdot community use for small office backups?