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Submission + - Whirlpool Refrigerator Service Repair Center Hyderabad Secunderabad (

sudhagoud writes: we at or Whirlpool Refrigerator Service Repair Center Hyderabad Secunderabad have the tech guys who can assist you in diagnosing your appliance that too with 100% precision. In today’s competitive and fraud filled market, there will be only very few service center people who concern about their customer’s appliance as their own in solving issues. And we are the one who stands top on that list. We’ve marked ourselves as the top service center people that provide Gas Refilling, Cooling Compres Ice Problem authenticity in our every work and accuracy in delivering the solutions for errors in Best Home appliances.

Submission + - First They Got Sick, Then They Moved Into a Virtual Utopia (

mirandakatz writes: At one point not too long ago, futurists believed that Second Life was the final frontier of social media. Today, the platform is well past its peak—but it continues to host a thriving community of people with disabilities, who are able to live in Second Life in ways they cannot offline. At Backchannel, Kristen French embeds in one such community on "Virtual Ability Island," and offers up a gloriously detailed look at the utopia its residents are creating for themselves. She writes, "For many disabled residents, who may spend 12 hours a day or more in Second Life, the most important moments and relationships of their lives happen inside the virtual world. For them, the fevered fantasies of a decade ago have become reality: Second Life is where they live."

Comment Re:If it were 10% false positives, excellent scree (Score 1) 99

and to add to my own post:

There are 17 diseases that the breath analyser detects, if each has a false positive rate of 10%, we have the following:
9999 * 17 = 169,983 false positives per 100,000 people per year.
It'd be like one of those kids' athletic competitions, everyone gets a prize.

Comment Re:If it were 10% false positives, excellent scree (Score 1) 99

I'm sorry, but a 10% false positive rate is terrible, especially for screening purposes.

For example:
Lets assume that a true diagnosis for disease X is at a rate of 10 in 100,000 people per year (fairly reasonable incidence rate for a lot of diseases).

Assuming there are no false negatives, the number of diagnoses that are made using the test will be:
Number of true positives + 10% of the true negatives

Number of true positives = 10
Number of true negatives = 99,990

# of diagnoses made = 10 + 0.10*99,990
= 10,009
The 9999 false positives would have to have further follow up tests and possibly erroneous treatment. This then of course puts a significant financial burden on the heathcare system.

Comment How is this different from the last 3 times? (Score 0) 277

They've tried it over:
and over:
and over again:

and failed:
and failed again:

What's different about this time around?

Comment Doesn't work for people who use the data either (Score 1) 326

I work in health informatics/epidemiology putting together and analysing large datasets for various eHealth projects (government, academia and private industry). The entire system of standardised data formats etc... that makes doctors' lives painful is, in many ways, supposed to make mine easier. Unfortunately nothing could be further from the truth.

Somewhere along the way the message has been lost, and from where I sit it's due to a lack of communication between clinicians, bean counters and IT people. Clinicians often have a rather arrogant view of the world. They tend to assume technology is easy and the only reason they can't do it is that they haven't been bothered yet. The don't treat IT professionals as being specialists in their own right. Rather, they treat them as service people, in much the same way as you would pay someone to mow your lawns (it's menial and I don't have the time blah blah...).

On the other hand IT professionals (the ones that do the UI stuff) rarely seem to understand or care why the data is being collected, just that it is. This of course leads them to make all sorts of assumptions that often turn out to be completely incorrect. One such system that I've seen had 2 options for gender, male and female. This system was supposed to be used in a urology department that often dealt with intersex people.

Finally we come to the bean counters, for some reason healthcare and healthcare IT seem to attract the worst of the worst PHBs which just compounds the entire problem.

Comment Re:When Patent Time Rolls Around ... (Score 1) 111

Over half of long term non progressors go on to lose their non-progressing status. The median time to losing LTNP status is 11 years.

For further information see: Madec Y et al. Early control of HIV-1 infection in long-term nonprogressors followed since diagnosis in the ANRS SEROCO/HEMOCO cohort. J AIDS 50: 19-26, 2009.

Comment Re:How is the person HIV positive? (Score 5, Informative) 111

That being said, there's a high probability that a vaccinated person would test as HIV positive today, because most HIV tests look for the antibodies, not the virus. Give them a vaccine that stimulates antivirus production...

This is not true, vaccinated people would not test HIV positive. first line HIV screens look for certain kinds of antibodies, the particular antibody the article is referring is not one of those antibodies.

The initial HIV screen is a combined antibody/antigen assay, if that is positive a follow up screen, called a Western Blot, is done. The western blot looks for additional antibodies, such as: p24, gag, pol etc... If enough of these bands are positive then the person is considered HIV positive. There are cases where a western blot can return as indeterminate, in some cases (like a grp IV) the person is most likely positive but may not be. Interestingly, with the introduction of post exposure prophylaxis many people are now returning indeterminate western blots and never fully sero-convert despite being HIV positive. In these cases pro-viral DNA is used as a diagnosis.

Comment Re:It will come back, though (Score 5, Informative) 126

No, there IS a large reservoir in the Thames Valley. Sorry.

And I never said it was dormant, I said that there was no vector to convert it to humans: mozzies. They need a certain amount of temperature for a minimum period of time for the parasite causing malaria in humans to grow to an infectious host in the mozquito.

I'm not sure if you're trolling or not, but I'll reply on the off chance you are just misinformed.

Plasomdium spp., the causal agent of malaria, lives in mosquitos and humans. It does not live anywhere else, not in the water or ground or air. It reproduces in humans and is spread to a mosquito when a person is bitten. The parasite is the re-transmitted back to a human when that mosquito bites again. The parasite does not require a certain temperature to grow to be infectious within the mosquito. The ONLY way the malaria parasite can be transmitted to a mosquito is via a human host. If no humans within a region have malaria, then there is no way for malaria transmission to occur, and thus no malaria.

Following on from this, if there is no malaria in humans, the only disease reservoir will be the mosquito. If there is 0 prevalence of malaria within a region for longer than the lifespan of a mosquito (typically ~50 days) the malaria parasite will be eliminated.

Comment Re:It will come back, though (Score 5, Informative) 126

No, there is not a large pool of the malaria parasite in the thames valley. This is a stupid statement. Malaria doesn't lie dormant in the environment, waiting for the right conditions to appear. It can only survive in the host or vector. The only place it can lie 'dormant' is within the human host. Given there have been no cases of malaria transmission in England for a very long time we can safely say that there is no 'large pool of the malaria microbe'. Your statement that winters being too cold to allow mosquito and parasite to mix together clearly indicates you've got no clue what you're talking about. The reason that cold weather prevents malaria is that the adult mosquitos are dead, only the eggs are present (and malaria doesn't live in mosquito eggs). If the adults are dead there are no transmission events because there are no mosquitos around to bite.

Submission + - Study of Brain Cancer and Cell Phones (

sosis96 writes: "Brain cancer cell phones – A new study out of Denmark suggests that cell phone use may not increase your risk of some types of noncancerous brain tumors. Apparently, it makes sense that if cell phone radiation caused tumor growth in humans, that this particular tumor might be found more often in people using cell phones."

Submission + - Copy & Paste: Large Scale DNA Editing Created (

smitty777 writes: Researchers at Harvard Medical School and MIT have collaborated to create a new simplified method for editing neucleotide sequences in DNA. The researchers have even dubbed it the "evolution machine" because of its ability to target specific changes in organisms. Two techniques were combined in order to accomplish this; multiplex automated genome engineering (MAGE) and a new technology called conjugative assembly genome engineering (CAGE).
Researcher Dr. Harris Wang states that "We're trying to challenge people to think about the genome as something that's highly malleable, highly editable". This technology could be used to establish multi-viral resistance by rewriting code hijacked by viruses or introducing cross-contamination safeguards between organisms.

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