Not available offline, but... (Score 2, Informative)

I've been using a great product called http://www.basecamphq.com/Basecamp. its only available on the web, but it allows collaboration, file uploading, and lots of features. There's also a company called Guavasoft that is developing an open source ERP suite similar to Compiere, only not just CRM and its a web-application. Kind of like salesforce.com but expanded.