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Comment Very rare disease (Score 1) 195

I was surprised they did this for the very rare B first instead of the more common A, no pharmaceutical company would go through expensive FDA trials to treat a rare disease when they can focus on the more common one first using the same technology. Then I realised that this is the rare strain the European royal family has.

Feels good when you can redirect the resources of the entire globe to solve your own person problems before everyone else's.

Comment Quality vs Quantity (Score 4, Interesting) 30

Most conferences I've seen are current accepting just about every submission they receive post-covid - a lot of people still aren't travelling which means less conference fees which means conference organisers are sad.

My heart bleeds for those poor conference organisers of course.

Quite surprising the story says about 400 papers were rejected. In the current environment, they must have been complete dross. Does anyone know which countries those 400 rejected papers came from? That would be more interesting to me.

Comment Re: And I want to lose weight in 2023. (Score 1) 46

I don't know your personal circumstances, but on average, at a population level, the body shape you have in your 40s is the body shape you have for the rest of you life. Every year you get older from that age, it becomes harder for you to make a change.

50s is still relatively young, so you have a good chance of not having developed any major issues yet.

But if your weight is high enough that you think about it, then not having developed major issues generally won't remain true through your 60s, 70s or 80s.

So for someone in their 50s, the time to make a change is always today and not tomorrow.

Comment Re:Is it just me? (Score 4, Interesting) 87

Yup - Lithium is more abundant in the earth's crust than Copper, Nickel, Lead, Chromium, Zinc, Silver and many more.

The only real problem is that it can take 9 years to get a mine up and running, and since there has been a step change in demand, there is a bit of lag on production.

$3M is probably only what I would call a mid-sized research grant - so it isn't like the Department of Energy is betting big money on this tech. Think of it as a bit of a side study to see if anything interesting comes up.

The "paradigm-shifting" quotes are just the standard academic professor big-noting their work to get funding and not worth paying attention to.

I'm a bit confused as to where the "Lithium is rare" quote comes from. I'm sure the US Department of Energy doesn't actually believe that.

Comment Incorrect net wealth calculations (Score 5, Insightful) 37

The way Bloomberg Terminal (and many others) calculate net worth is always wildly optimistic as it doesn't take into account market depth.

On any given day, only a fraction of the total market capitalization of stock is traded, and basic laws of supply and demand dictate the price of that stock.

Then Bloomberg takes that stock price, multiplies it by the number of shares a particular person has, then claims that is their net worth.

But for big whales who own more shares than the daily, weekly or monthly market volumes, if they were to actually sell their shares, then they would massively suppress the price as they would increase the supply, and there would likely be no one in the market to take up demand at the current price.

Bankman-Fried was never going to be able to sell all his units of FTX for $16B. Even now, he can't actually sell all his units of FTX for $991 million. These numbers are almost completely fictional, with only the lightest shoestring tie to reality.

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