Best Patch Management Software for Microsoft 365

AssetSonar's Patch Management solution enhances the security of your IT infrastructure by actively identifying vulnerabilities on Windows, macOS, and Linux systems in real-time. Utilizing agent-based monitoring, it pinpoints risks and directly associates them with the relevant hardware and software. With prioritized patch recommendations, IT teams can concentrate on the most critical issues. You have the flexibility to deploy or schedule patches on a large scale, monitor success and failure metrics, and maintain compliance with standards such as NIST through integrated dashboards. By incorporating patch management into its comprehensive IT asset management workflows, AssetSonar minimizes blind spots, reduces manual tasks, and instills confidence in IT leaders that all endpoints are secure and prepared for audits.

Iru AI reimagines enterprise security and IT management with a unified, AI-driven platform that eliminates tool fragmentation and operational overhead. At its core is the Iru Context Model, a dynamic intelligence layer that connects identity, endpoint, and compliance management into one cohesive ecosystem. The platform offers passwordless authentication, device-bound access policies, and real-time vulnerability detection—creating a trust fabric that safeguards every user and device. Iru’s endpoint suite integrates management, detection, and response capabilities across Apple, Windows, and Android environments for holistic protection. Its Compliance Automation engine continuously maps and updates controls, ensuring organizations remain audit-ready while accelerating deal cycles. By merging automation with contextual intelligence, Iru empowers IT and security teams to make faster, smarter decisions. Companies gain a consolidated view of their infrastructure, reducing zero-day exploit risks and boosting productivity across teams. With a 4.75/5 G2 rating and adoption by thousands of high-growth enterprises, Iru delivers a future-ready foundation for secure, intelligent business operations.

SysAid is an AI-first ITSM and Help Desk platform designed to make IT teams more efficient. Powered by Agentic AI, it accelerates issue resolution, automates repetitive tasks, and helps IT shift from firefighting to driving strategic impact. With no-code workflows, AI-powered ticket handling, and a modern self-service portal, SysAid lets your team focus on what matters most—delivering business value. At the core is Agentic AI: a powerful operational layer where AI Agents take the first action—boosting efficiency and speeding up resolutions. SysAid is built with enterprise-grade security, governance, and responsible AI—complete with customizable guardrails and controls. Go live in weeks with fast, code-free onboarding—no complex migrations or steep learning curves. Flexible, scalable, and supported by award-winning service, SysAid is ITSM run by AI—and by you.

Automate the entire patching process with Patch Manager Plus to keep all your production businesses current. Patch Manager Plus is available as both cloud-based software and on-premise software. It features features such as automatic scheduled patch deployments, scanning for missing patches, approval testing, patch tracking, patch compliance, reporting, and patch tracking. Patch Manager Plus allows users to create detailed audit and compliance reports.

KACE is an endpoint management solution that offers a single point of control for managing IT systems across the entire organization. From initial deployment to ongoing maintenance, KACE is designed to fulfill all endpoint security and deployment needs—helping businesses quickly deploy, monitor, and manage their devices using a unified inventory database. KACE improves device security with on-demand hardware and software discovery, patch management, compliance reporting, and real-time monitoring of mobile endpoints. KACE is a Unified Endpoint Management solution that offers a single point of control for managing IT systems across the entire organization, inside or outside your network. This comprehensive solution takes the stress out of keeping devices secure and compliant so you can do more. Unified Endpoint Management by KACE. Where Next Meets Now.

Put your devices on auto-pilot. Fleetsmith automates the setup, intelligence, patching and security of your company's Macs and iPhones, iPads and Apple TVs. Automated setup of devices for new hires Check. Automated detection and prevention of problems across your fleet Yup. You can automatically install and update apps. You bet. Every aspect of our product and every decision we make is based on security. We have made sure that our product is secure from the beginning, as well as our internal policies, based on our company value of "Secure by Design". One-click sign-up, single sign-on (SSO) and import of your employee directory are all possible. All this with zero configuration.

ESET PROTECT Elite serves as a top-tier cybersecurity platform designed for enterprises, seamlessly combining extensive detection and response capabilities with a robust multilayered defense system. Utilizing cutting-edge techniques like adaptive scanning, machine learning, cloud sandboxing, and behavioral analysis, it effectively combats zero-day vulnerabilities and ransomware threats. The solution delivers modern endpoint protection for both computers and mobile devices, along with server security that ensures real-time data safety and mobile threat defense. Additionally, it incorporates full disk encryption, which aids organizations in meeting data protection compliance requirements. ESET PROTECT Elite also boasts powerful email security features that encompass anti-phishing, anti-malware, and anti-spam measures, while providing protection for cloud applications such as Microsoft 365 and Google Workspace. Its vulnerability management and patch capabilities automate the identification and remediation of security flaws across all endpoints, fostering a proactive approach to cybersecurity. Overall, ESET PROTECT Elite is a comprehensive solution that addresses the evolving challenges of modern cybersecurity threats.

Transform your Digital Workplace management with the Juriba Platform, a revolutionary Digital Platform Conductor (DPC) designed exclusively for the dynamic needs of enterprise-level Digital Workplace leaders. Embrace a comprehensive range of capabilities, from end-to-end Digital Workplace management to application testing and packaging, as well as driving complex IT transformations and Evergreen IT management initiatives. Integrating seamlessly with leading Hybrid Digital Infrastructure Management tools like Microsoft Endpoint Manager, Microsoft Intune, ServiceNow, NexThink, and Workspace ONE, the Juriba Platform ensures seamless data synchronization across your entire Digital Workplace, granting you unparalleled visibility and control. By harnessing intelligent workplace automation and orchestration, mundane tasks are automated, freeing up valuable time and reducing the risk of human error. Unlock the true potential of your IT environment with user-friendly dashboards and reports that offer in-depth insights, empowering you to make data-driven decisions that optimize infrastructure investments and drive business growth.

Automate patch assessment, monitoring, remediation. Your staff will be able to apply patches up 13 times faster than before. You can create team workspaces that allow you to connect local and global team members online to coordinate their efforts. Monitor patch compliance, quickly assess vulnerabilities and apply patches to meet pre-defined standards. Patch Management monitors your network 24/7 and automatically patches all vulnerabilities. ZENworks' unique policy-based approach lets you set up policies and define the actions. Then, just sit back and let ZENworks take care of the rest. ZENworks Patch Management allows for fast, automatic patch deployments based on predefined policies. You can also customize patches as required. It supports phased rollouts, which ensure smooth, error-free patches deployments to large systems.

Datto RMM, a cloud-based remote monitoring platform and management platform that provides MSPs with the ability to secure and reliably manage customers' IT infrastructures, is reliable, modern and reliable. It was designed to reduce complexity, costs, risks, and risk. It includes powerful automation tools and monitoring tools like ransomware detection, patch management and remote control takeover. This allows MSPs to prevent IT problems, respond quickly to incidents, and provide better service to customers. All-in-one, reliable cloud backup and disaster recovery that is image-based. Cloud-to-cloud backup, fast recovery of critical data in Microsoft 365 or G Suite applications. Support for Windows and Mac allows for fast file and folder backups and restores. Secure file sync and sharing with a centrally managed, secure collaboration system. Servers can be quickly and reliably restored using an image-based, all in one business continuity and disaster recovery solution.

Windows Autopatch is a cloud-based service from Microsoft designed to automate the process of delivering and managing updates for Windows, Microsoft 365 Apps for enterprise, Microsoft Edge, and Microsoft Teams, thereby enhancing security, maintaining productivity, and lessening the administrative burden on an organization’s devices. By ensuring that systems are up-to-date with the latest quality and feature enhancements, it effectively addresses security vulnerabilities and facilitates the adoption of new tools as they become available, allowing IT staff to redirect their efforts towards more strategic initiatives rather than routine update management. Autopatch also minimizes interruptions for end-users by implementing phased rollout strategies and sequential deployment rings that adapt to feedback on reliability and compatibility, thereby lowering the risk of widespread disruptions while keeping stakeholders informed about the update process. In doing so, it not only streamlines the update process but also contributes to a more efficient and secure IT ecosystem within organizations.