ESMFold2 Description
ESMFold2 builds upon its predecessor, ESMFold, by establishing a new benchmark in single-sequence structure prediction and facilitating the creation of novel functional proteins via exploration of the latent space within the ESMC model. This advanced model is capable of forecasting high-resolution, all-atom 3D structures of biomolecular complexes straight from the amino acid sequence, and it allows for the incorporation of multiple sequence alignments to improve accuracy on difficult targets. Tailored for predicting structures through both sequence and structure modalities, it employs ESM representations that drive a series of looped folding layers while a diffusion model translates pairwise representations into atomic-resolution outcomes. ESMFold2 excels in predicting protein structures from amino acid sequences, providing detailed structural data, including precise all-atom coordinates for both backbone and side chains, along with confidence metrics and optional distogram predictions for in-depth structural evaluation. Furthermore, its innovative approach enhances the understanding of protein folding dynamics and functional implications, making it a valuable tool for researchers in the field.
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Biohub
Biohub serves as an accessible platform dedicated to advancing the understanding of protein biology. It offers users the ESM model family, which includes ESMC, ESMFold2, and ESM3, alongside interactive tools and resources tailored for developers involved in protein science research. ESMC stands out as a cutting-edge protein language model, meticulously trained on vast amounts of evolutionary sequence data, allowing it to create representations that elucidate key mechanisms underlying protein structure and function. This model facilitates various applications such as functional analysis, predicting structures, designing proteins, and investigating the evolutionary connections among different proteins. Meanwhile, ESMFold2 specializes in predicting high-resolution, all-atom 3D structures of biomolecular complexes from sequences, while offering the option of including multiple sequence alignments to improve accuracy for difficult targets. Additionally, ESM3 takes a holistic approach by simultaneously modeling sequence, structure, and function, thus enabling the generation of innovative proteins through conditioning on a blend of these aspects. This unique integration of tools and models empowers researchers to explore new frontiers in protein science.
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FLUX 3
FLUX 3 is an advanced multimodal foundation model that integrates learning from images, video, and audio all within a cohesive framework, effectively modeling how objects connect, how movements occur, and how events produce sound. Utilizing the Self-Flow methodology, it harmonizes the generation and comprehension of multiple modalities in a singular architecture, ensuring that each modality influences the others—sound corresponds to impact, motion adheres to physical laws, and future occurrences are informed by past events. This model is capable of blending modalities, allowing for the simultaneous generation of images, video, and authentic audio based on text prompts or references such as visual and auditory inputs. Its video functionalities are extensive, featuring text-to-video capabilities, image-driven video animation, video transformation, generative continuation of video and audio, controlled transitions using keyframes, multilingual dialogue support, animated text design, and the ability to deliver various styles and aspect ratios, alongside the capacity for agentic chaining into intricate, longer multi-shot sequences. Additionally, FLUX 3 represents a significant leap forward in the field of multimodal AI, offering unprecedented flexibility and creativity in generating rich, interactive content.
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Pricing
Pricing Starts At:
Free
Free Version:
Yes
Company Details
Company:
Biohub
Year Founded:
2016
Headquarters:
United States
Website:
biohub.ai/models/esmfold2
Media
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Product Details
Platforms
Web-Based
Types of Training
Training Docs
Customer Support
Online Support
ESMFold2 Features and Options
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