ESMFold2 Description

ESMFold2 builds upon its predecessor, ESMFold, by establishing a new benchmark in single-sequence structure prediction and facilitating the creation of novel functional proteins via exploration of the latent space within the ESMC model. This advanced model is capable of forecasting high-resolution, all-atom 3D structures of biomolecular complexes straight from the amino acid sequence, and it allows for the incorporation of multiple sequence alignments to improve accuracy on difficult targets. Tailored for predicting structures through both sequence and structure modalities, it employs ESM representations that drive a series of looped folding layers while a diffusion model translates pairwise representations into atomic-resolution outcomes. ESMFold2 excels in predicting protein structures from amino acid sequences, providing detailed structural data, including precise all-atom coordinates for both backbone and side chains, along with confidence metrics and optional distogram predictions for in-depth structural evaluation. Furthermore, its innovative approach enhances the understanding of protein folding dynamics and functional implications, making it a valuable tool for researchers in the field.

Pricing

Pricing Starts At:
Free
Free Version:
Yes

Integrations

API:
Yes, ESMFold2 has an API

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Company Details

Company:
Biohub
Year Founded:
2016
Headquarters:
United States
Website:
biohub.ai/models/esmfold2

Media

ESMFold2 Screenshot 1
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Product Details

Platforms
Web-Based
Types of Training
Training Docs
Customer Support
Online Support

ESMFold2 Features and Options

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