LM-Kit.NET is an enterprise-grade toolkit designed for seamlessly integrating generative AI into your .NET applications, fully supporting Windows, Linux, and macOS. Empower your C# and VB.NET projects with a flexible platform that simplifies the creation and orchestration of dynamic AI agents.
Leverage efficient Small Language Models for on‑device inference, reducing computational load, minimizing latency, and enhancing security by processing data locally. Experience the power of Retrieval‑Augmented Generation (RAG) to boost accuracy and relevance, while advanced AI agents simplify complex workflows and accelerate development.
Native SDKs ensure smooth integration and high performance across diverse platforms. With robust support for custom AI agent development and multi‑agent orchestration, LM‑Kit.NET streamlines prototyping, deployment, and scalability—enabling you to build smarter, faster, and more secure solutions trusted by professionals worldwide.
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SciSure is reshaping the future of laboratories worldwide with forward-thinking digital solutions. Our Digital Lab Platform (DLP) unites key tools such as Electronic Lab Notebook (ELN), Laboratory Information Management Systems (LIMS), and advanced technologies like AI and machine learning. Built for seamless compatibility with your lab's hardware and software, the platform enhances flexibility, security, and efficiency. By consolidating and optimizing your research and development workflows within a secure and compliant environment, we help researchers dedicate more time to innovation. Our expert team is committed to supporting you at every stage of your digital lab transformation.
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Biohub
Biohub serves as an accessible platform dedicated to advancing the understanding of protein biology. It offers users the ESM model family, which includes ESMC, ESMFold2, and ESM3, alongside interactive tools and resources tailored for developers involved in protein science research. ESMC stands out as a cutting-edge protein language model, meticulously trained on vast amounts of evolutionary sequence data, allowing it to create representations that elucidate key mechanisms underlying protein structure and function. This model facilitates various applications such as functional analysis, predicting structures, designing proteins, and investigating the evolutionary connections among different proteins. Meanwhile, ESMFold2 specializes in predicting high-resolution, all-atom 3D structures of biomolecular complexes from sequences, while offering the option of including multiple sequence alignments to improve accuracy for difficult targets. Additionally, ESM3 takes a holistic approach by simultaneously modeling sequence, structure, and function, thus enabling the generation of innovative proteins through conditioning on a blend of these aspects. This unique integration of tools and models empowers researchers to explore new frontiers in protein science.
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ESMFold2
ESMFold2 builds upon its predecessor, ESMFold, by establishing a new benchmark in single-sequence structure prediction and facilitating the creation of novel functional proteins via exploration of the latent space within the ESMC model. This advanced model is capable of forecasting high-resolution, all-atom 3D structures of biomolecular complexes straight from the amino acid sequence, and it allows for the incorporation of multiple sequence alignments to improve accuracy on difficult targets. Tailored for predicting structures through both sequence and structure modalities, it employs ESM representations that drive a series of looped folding layers while a diffusion model translates pairwise representations into atomic-resolution outcomes. ESMFold2 excels in predicting protein structures from amino acid sequences, providing detailed structural data, including precise all-atom coordinates for both backbone and side chains, along with confidence metrics and optional distogram predictions for in-depth structural evaluation. Furthermore, its innovative approach enhances the understanding of protein folding dynamics and functional implications, making it a valuable tool for researchers in the field.
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