ESMC Description
ESMC represents the newest advancement in the ESM series of protein language models, pushing the boundaries of representation learning within the field of protein biology. With training on billions of evolutionary sequences, it adeptly captures representations that encapsulate a mechanistic understanding of protein structure and function. The model utilizes a transformer architecture, focusing on sequences as its primary modality, and is trained on a vast dataset comprising up to 6 billion proteins. ESMC is tailored for various protein science applications, such as predicting structures, annotating functions, designing proteins, and exploring evolutionary connections among proteins. Additionally, it possesses the capability to create novel proteins based on partial sequences, structures, or functional constraints, thereby enabling researchers to investigate innovative avenues in protein design and biological discovery. Accessible through the Biohub Platform, ESMC can be utilized via an API and the ESM Python package, which includes quickstart resources for installation, API key generation, and platform connectivity, ensuring a seamless experience for users. This comprehensive accessibility encourages a broader engagement with protein research and enhances collaborative efforts in the scientific community.
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Evo 2
Evo 2 represents a cutting-edge genomic foundation model that excels in making predictions and designing tasks related to DNA, RNA, and proteins. It employs an advanced deep learning architecture that allows for the modeling of biological sequences with single-nucleotide accuracy, achieving impressive scaling of both compute and memory resources as the context length increases. With a robust training of 40 billion parameters and a context length of 1 megabase, Evo 2 has analyzed over 9 trillion nucleotides sourced from a variety of eukaryotic and prokaryotic genomes. This extensive dataset facilitates Evo 2's ability to conduct zero-shot function predictions across various biological types, including DNA, RNA, and proteins, while also being capable of generating innovative sequences that maintain a plausible genomic structure. The model's versatility has been showcased through its effectiveness in designing operational CRISPR systems and in the identification of mutations that could lead to diseases in human genes. Furthermore, Evo 2 is available to the public on Arc's GitHub repository, and it is also incorporated into the NVIDIA BioNeMo framework, enhancing its accessibility for researchers and developers alike. Its integration into existing platforms signifies a major step forward for genomic modeling and analysis.
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Claude Mythos 5
Claude Mythos 5 is a frontier AI model from Anthropic created for highly trusted users working on advanced cybersecurity, infrastructure protection, and scientific research. It is based on the same core model as Claude Fable 5, but certain safeguards are lifted for approved partners operating under restricted access programs. The model offers exceptional performance across software engineering, cybersecurity analysis, autonomous development workflows, scientific reasoning, visual understanding, and long-context tasks. In cybersecurity, Claude Mythos 5 is positioned for cyberdefenders and critical infrastructure providers who need advanced AI support for securing complex systems. In life sciences, the model has demonstrated strong capabilities in drug design, protein research, molecular biology, and genomics. Claude Mythos 5 can perform long-running research and technical workflows with minimal high-level human input. Anthropic designed the model for controlled deployment because its advanced capabilities could create misuse risks if broadly available without safeguards. Access is initially limited to Project Glasswing partners, with broader trusted access programs planned for cybersecurity and select biology researchers. Claude Mythos 5 helps approved organizations apply powerful AI to high-impact technical and scientific challenges while operating within a stricter governance model.
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Pricing
Pricing Starts At:
Free
Free Version:
Yes
Company Details
Company:
Biohub
Year Founded:
2016
Headquarters:
United States
Website:
biohub.ai/models/esmc
Media
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Product Details
Platforms
Web-Based
Types of Training
Training Docs
Customer Support
Online Support
ESMC Features and Options
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