Best Endpoint Protection Software for Microsoft 365

Find and compare the best Endpoint Protection software for Microsoft 365 in 2026

Use the comparison tool below to compare the top Endpoint Protection software for Microsoft 365 on the market. You can filter results by user reviews, pricing, features, platform, region, support options, integrations, and more.

  • 1
    Guardz Reviews
    See Software
    Learn More
    Guardz is the unified cybersecurity platform purpose-built for MSPs. We consolidate the essential security controls, including identities, endpoints, email, awareness, and more, into one AI-native framework designed for operational efficiency. Our identity-centric approach connects the dots across vectors, reducing the gaps that siloed tools leave behind so MSPs can respond to user risk in real time. With 24/7 AI + human-led MDR, Guardz utilizes agentic AI to triage at machine speed while expert analysts validate, mitigate, and guide response, giving MSPs scalable protection without adding headcount.
  • 2
    Iru Reviews

    Iru

    Iru (formerly Kandji)

    1,282 Ratings
    See Software
    Learn More
    Iru AI reimagines enterprise security and IT management with a unified, AI-driven platform that eliminates tool fragmentation and operational overhead. At its core is the Iru Context Model, a dynamic intelligence layer that connects identity, endpoint, and compliance management into one cohesive ecosystem. The platform offers passwordless authentication, device-bound access policies, and real-time vulnerability detection—creating a trust fabric that safeguards every user and device. Iru’s endpoint suite integrates management, detection, and response capabilities across Apple, Windows, and Android environments for holistic protection. Its Compliance Automation engine continuously maps and updates controls, ensuring organizations remain audit-ready while accelerating deal cycles. By merging automation with contextual intelligence, Iru empowers IT and security teams to make faster, smarter decisions. Companies gain a consolidated view of their infrastructure, reducing zero-day exploit risks and boosting productivity across teams. With a 4.75/5 G2 rating and adoption by thousands of high-growth enterprises, Iru delivers a future-ready foundation for secure, intelligent business operations.
  • 3
    Rippling Reviews

    Rippling

    Rippling

    $8 PEPM
    19,366 Ratings
    See Software
    Learn More
    Say goodbye to the chaos of managing various tools for identity, access, devices, and inventory. With Rippling, everything is consolidated into a single, cohesive platform that leverages comprehensive employee data for seamless integration. Streamline tedious manual processes such as device configuration, access granting, endpoint oversight, and offboarding with just a few clicks. Gain full insight into users and equipment, proactively address security vulnerabilities before they escalate, and achieve this without the necessity of expanding your workforce. Experience the quickest route to a scalable and secure IT environment—free from tool overload and excessive costs.
  • 4
    Syncro Reviews
    Top Pick

    Syncro

    Syncro

    $129 per user per month
    25 Ratings
    Syncro is the integrated business platform for running a profitable MSP. Enjoy PSA, RMM, and remote access in one affordable package. PLUS! Integrations to 50+ MSP and business tools you also love and use amp your efficiency even more. Syncro pricing is refreshingly simple—one flat fee for all PSA, RMM, and remote access features. Unlimited endpoints, no contracts, no minimums.
  • 5
    ManageEngine Patch Manager Plus Reviews
    Automate the entire patching process with Patch Manager Plus to keep all your production businesses current. Patch Manager Plus is available as both cloud-based software and on-premise software. It features features such as automatic scheduled patch deployments, scanning for missing patches, approval testing, patch tracking, patch compliance, reporting, and patch tracking. Patch Manager Plus allows users to create detailed audit and compliance reports.
  • 6
    Electric Reviews
    Electric is changing the way businesses manage IT. Electric provides real-time IT support for over 30,000 users and central IT management to more than 600 customers. This offers companies a 50% savings in IT costs and standardized security across devices, apps and networks.
  • 7
    ConnectWise Cybersecurity Management Reviews
    ConnectWise Cybersecurity Management (formerly ConnectWise Fortify) software and support solutions help MSPs protect their clients’ critical business assets. From 24/7 threat detection monitoring, incident response, and security risk assessment tools, ConnectWise Cybersecurity Management solutions remove the complexity associated with building an MSP-powered cybersecurity stack and lower the costs of 24/7 monitoring support staff.
  • 8
    KACE by Quest Reviews

    KACE by Quest

    Quest Software

    As low as $3/mo/device
    2 Ratings
    KACE is an endpoint management solution that offers a single point of control for managing IT systems across the entire organization. From initial deployment to ongoing maintenance, KACE is designed to fulfill all endpoint security and deployment needs—helping businesses quickly deploy, monitor, and manage their devices using a unified inventory database. KACE improves device security with on-demand hardware and software discovery, patch management, compliance reporting, and real-time monitoring of mobile endpoints. KACE is a Unified Endpoint Management solution that offers a single point of control for managing IT systems across the entire organization, inside or outside your network. This comprehensive solution takes the stress out of keeping devices secure and compliant so you can do more. Unified Endpoint Management by KACE. Where Next Meets Now.
  • 9
    JumpCloud Reviews
    Small and medium-sized enterprises (SMEs) around the world can realize true freedom of choice by partnering with JumpCloud. JumpCloud centralizes the management and security of identities, access, and devices through its cloud-based open directory platform, enabling IT teams and managed service providers (MSPs) to remotely support Windows, Mac, Linux, and Android devices, manage identities natively or from their preferred HRIS or productivity suite, and provide access to hundreds of on-prem and cloud-based apps with a single, secure set of credentials. Start a 30 Day Trial of JumpCloud today to take advantage of the entire platform for free.
  • 10
    WithSecure Elements XDR Reviews
    WithSecure's modular Elements Cloud cyber security platform seamlessly integrates Extended Detection and Response (XDR), Exposure Management (XM) and Co-Security Services into a single unified solution. - WithSecure Elements XDR includes Elements Endpoint Security (your EPP+EDR), Identity Security for Microsoft Entra ID, Collaboration Protection for Microsoft 365, and Cloud Security for Azure as modules. You can flexibly choose which capabilities to include in your Elements XDR solution. - WithSecure Elements Exposure Management (XM) is a continuous and proactive solution that predicts and prevents breaches against your company’s assets and business operations. Elements XM provides visibility into your attack surface and enables the efficient remediation of its highest-impact exposures through a unified view, thanks to our exposure scoring and AI-enabled recommendations. Get one solution for 360° digital exposure management and visibility across your external attack surface and internal security posture, to proactively prevent cyber-attacks. Through our flexible Elements modules made of cutting-edge software and high-quality services, customers can find the optimal solution for their needs. Together, the modules offer end-to-end business and cloud coverage. In today's unpredictable, ever-changing business environment, our all-in-one security platform helps you build and maintain a resilient business. We believe in the European Way of cyber security and we do this together with our partners as the Elements Cloud is really geared to enable WithSecure’s partners to offer robust security products and managed security services to mid-sized and other resource constrained companies.
  • 11
    Defense.com Reviews

    Defense.com

    Defense.com

    $30 per node per month
    Take charge of your cyber threats effectively by utilizing Defense.com to identify, prioritize, and monitor all your security risks in one streamlined platform. Simplify your approach to cyber threat management with integrated features for detection, protection, remediation, and compliance, all conveniently consolidated. By leveraging automatically prioritized and tracked threats, you can make informed security decisions that enhance your overall defense. Improve your security posture by adhering to proven remediation strategies tailored for each identified threat. When challenges arise, benefit from the expertise of seasoned cyber and compliance consultants who are available to provide guidance. Harness user-friendly tools that seamlessly integrate with your current security investments to strengthen your cyber defenses. Experience real-time insights from penetration tests, vulnerability assessments, threat intelligence, and more, all displayed on a central dashboard that highlights your specific risks and their severity levels. Each threat is accompanied by actionable remediation advice, facilitating effective security enhancements. Additionally, your unique attack surface is mapped to powerful threat intelligence feeds, ensuring that you are always one step ahead in the ever-evolving landscape of cyber security. This comprehensive approach enables you to not only address current threats but also anticipate future challenges in your security strategy.
  • 12
    ESET PROTECT Elite Reviews

    ESET PROTECT Elite

    ESET

    $275 one-time payment
    ESET PROTECT Elite serves as a top-tier cybersecurity platform designed for enterprises, seamlessly combining extensive detection and response capabilities with a robust multilayered defense system. Utilizing cutting-edge techniques like adaptive scanning, machine learning, cloud sandboxing, and behavioral analysis, it effectively combats zero-day vulnerabilities and ransomware threats. The solution delivers modern endpoint protection for both computers and mobile devices, along with server security that ensures real-time data safety and mobile threat defense. Additionally, it incorporates full disk encryption, which aids organizations in meeting data protection compliance requirements. ESET PROTECT Elite also boasts powerful email security features that encompass anti-phishing, anti-malware, and anti-spam measures, while providing protection for cloud applications such as Microsoft 365 and Google Workspace. Its vulnerability management and patch capabilities automate the identification and remediation of security flaws across all endpoints, fostering a proactive approach to cybersecurity. Overall, ESET PROTECT Elite is a comprehensive solution that addresses the evolving challenges of modern cybersecurity threats.
  • 13
    Microsoft Defender for Business Reviews
    Microsoft Defender for Business offers advanced, AI-powered cybersecurity protection built specifically for small and medium-sized organizations. It consolidates multiple security capabilities into a single solution, reducing costs while improving protection. The platform safeguards devices against ransomware, malware, phishing, and emerging threats across major operating systems. Built-in vulnerability management helps businesses discover and fix misconfigurations before they can be exploited. AI-powered endpoint detection and response works continuously to detect attacks and automatically stop them. Automated investigation and remediation reduce the need for manual security intervention. Defender for Business supports both office-based and remote employees with consistent device protection. Wizard-based setup and out-of-the-box security policies simplify deployment and management. Monthly security reports provide visibility into threats and overall security posture. Microsoft Defender for Business delivers enterprise-level protection without enterprise-level complexity.
  • 14
    OfficeScan Reviews
    The security landscape has evolved from a clear distinction between threats to a more complex scenario where identifying harmful elements is challenging. In today’s environment, relying solely on traditional signature-based antivirus solutions is inadequate, particularly when it comes to defending against ransomware and emerging threats that often evade detection. While next-generation technologies can mitigate certain risks, they are not universally effective, and deploying numerous anti-malware tools on a single endpoint can result in a disjointed system that fails to collaborate effectively. Adding to this complexity, users now access corporate resources from a multitude of devices and locations, including various cloud services. Therefore, it is essential to adopt endpoint security that is intelligent, streamlined, and cohesive, provided by a reputable vendor. Trend Micro™ OfficeScan™ integrates advanced machine learning with a variety of threat protection strategies to close security gaps across all user activities and endpoints, ensuring robust defense against modern cyber threats. This comprehensive approach not only enhances security but also simplifies management for IT teams navigating today’s challenging threat landscape.
  • 15
    Trend Micro ServerProtect Reviews
    Enterprise servers often serve as a centralized hub for information exchange, making them susceptible to vulnerabilities. Even within the confines of a secure network, users or applications lacking sufficient protection might inadvertently upload compromised files to the server, which can then propagate to other connected systems accessing those files. Furthermore, large organizations can operate hundreds or even thousands of individual servers that necessitate constant monitoring, configuration, and upkeep. Today's advanced cyber threats are capable of exploiting multiple network points, leaving behind hidden damage and creating risks for re-infection. Trend Micro™ ServerProtect™ offers robust protection against viruses, spyware, and rootkits while enhancing the efficiency of security operations on servers. This software not only scans and detects malware in real-time but also includes capabilities for cleaning up and repairing the system from any malicious code. By streamlining these processes, ServerProtect ensures that organizations can maintain a higher level of security and minimize potential disruptions.
  • 16
    Digital Guardian Reviews
    Uncompromised data protection offers the adaptability necessary to meet your specific requirements. Digital Guardian stands out among data loss prevention (DLP) solutions due to its capability to implement either a use case-based strategy (focusing on defined data types or user segments) or a data risk discovery methodology (which identifies previously unknown use cases). By utilizing this risk discovery framework, you can achieve enhanced visibility into the locations of sensitive data, its movement within the organization, and potential vulnerabilities, all without needing to establish policies. Built on AWS, Digital Guardian facilitates straightforward deployment, minimal overhead, and flexible scalability, maximizing the return on your security investment. It provides comprehensive support for Windows, macOS, Linux operating systems, and all types of applications, whether they are browser-based or native. Moreover, its unique “unknown risk” strategy further illuminates the whereabouts of sensitive data, detailing its movement and associated risks, again without relying on policies. Only Digital Guardian offers an integrated approach to data discovery and classification that encompasses content, user, and contextual factors, ensuring robust protection across your entire digital landscape. This multifaceted approach not only enhances data security but also streamlines compliance efforts across diverse regulatory environments.
  • 17
    Arctic Wolf Reviews
    Arctic Wolf is a cybersecurity platform that provides AI-powered protection combined with expert-led security services to help organizations manage and reduce cyber risk. At the core of its offering is the Aurora Platform, an open XDR system that unifies security operations across endpoints, cloud environments, and networks. The platform continuously monitors activity, detects threats, and enables rapid response to potential security incidents. Arctic Wolf also offers a concierge delivery model, providing organizations with ongoing guidance and support from security professionals. This approach ensures that businesses are not only equipped with technology but also have expert assistance to handle evolving threats. The platform supports a wide range of security needs, including managed detection and response, cloud security, risk management, and incident response. Arctic Wolf emphasizes proactive security by identifying vulnerabilities and mitigating risks before they lead to breaches. With extensive integrations and partnerships, it connects seamlessly with existing systems and tools. By combining automation, intelligence, and human expertise, Arctic Wolf helps organizations improve their security posture and reduce the likelihood of cyberattacks.
  • 18
    SilverSky Managed Security Services Reviews
    As cyber threats continue to accelerate and diversify through emerging security vectors, the complexity, skill, and resources required to counteract these risks are also rapidly escalating. This increasing complexity can leave security teams feeling overwhelmed and struggling to keep up. For over two decades, SilverSky has adapted as a managed security service provider, catering to the security and regulatory demands of small and mid-sized businesses with straightforward and affordable solutions. We focus on supporting industries that are subject to stringent regulations. Relying solely on perimeter firewalls for monitoring is now inadequate; organizations must oversee every point of contact within their infrastructure. This comprehensive monitoring encompasses networks, servers, databases, personnel, and endpoints. The most effective method for achieving this level of oversight is through a professionally staffed Security Operations Center, or SOC as a service. SilverSky Security Monitoring is dedicated to overseeing both perimeter and core security devices, ensuring that businesses not only meet but exceed regulatory compliance standards while enhancing their overall security posture. Our commitment to excellence means we continuously adapt our strategies to stay ahead of evolving threats.
  • 19
    Symantec Integrated Cyber Defense Reviews
    The Symantec Integrated Cyber Defense (ICD) Platform offers a comprehensive suite of security solutions, including Endpoint Security, Identity Security, Information Security, and Network Security, effectively safeguarding both on-premises and cloud environments. As the pioneering company to unify and synchronize security functions across these diverse systems, Symantec empowers organizations to adopt cloud technologies at their own pace while preserving prior investments in critical infrastructure. Understanding that organizations often utilize multiple vendors, Symantec has developed the Integrated Cyber Defense Exchange (ICDx), facilitating seamless integration of third-party solutions and intelligence sharing throughout the platform. Unique in the cyber defense landscape, Symantec provides robust solutions that cater to all types of infrastructures, whether they are fully on-premises, exclusively cloud-based, or a hybrid of both, ensuring adaptable protection for every enterprise. This commitment to flexibility and integration underscores Symantec's position as an industry leader in comprehensive cyber defense.
  • 20
    Becrypt Reviews
    Endpoint devices must maintain a high level of security to prevent any compromises. Organizations dealing with increased threats require products and services that offer high assurance. These solutions are designed for various devices, including desktops, laptops, and thin clients. The foundations of these architectures are rooted in research and development supported by government initiatives. A range of offerings, from managed services to security monitoring and specialized research and development, are available. Implementing zero trust architectures can significantly enhance the protection of cloud and online services by integrating assessments of device health and identity for service access. Allowing access to corporate resources from unmanaged endpoints often introduces significant supply chain risks. By focusing on robust device health and identity management, organizations can effectively mitigate third-party IT vulnerabilities. Additionally, established cloud and mobile architectures can be provided through managed services to facilitate secure collaboration with third-party entities, ensuring that security remains a priority in all interactions. This comprehensive approach not only safeguards data but also fosters a more resilient operational environment.
  • 21
    activeDEFENCE Reviews
    Threats to your organization's infrastructure are increasingly relentless, ranging from malware and advanced persistent threats (APTs) to extortion and internal breaches. In the modern business landscape, it is essential to account for the proliferation of smartphones, tablets, and the consumerization of IT, in addition to the complexities introduced by telecommuters, contractors, partners, and critical services hosted in the cloud. The importance of robust security measures has escalated, becoming more intricate than ever before. To effectively safeguard your information and systems, an adaptable and multi-layered defensive strategy is necessary, covering all aspects of your IT environment, including the network, perimeter, data, applications, and endpoints, while also addressing and managing vulnerabilities that could expose your organization to potential risks. activereach offers a comprehensive portfolio of network security solutions designed to shield your business from evolving threats, improve network performance, and enhance operational efficiencies, ensuring a more secure and resilient infrastructure. As the digital landscape continues to evolve, staying proactive in security measures is crucial for long-term success.
  • 22
    WinMagic MagicEndpoint Reviews
    MagicEndpoint offers the most secure user authentication with the best possible user experience. Once the user has unlocked the endpoint, the endpoint gives access to everything else — no user action required. Based on cutting-edge FIDO2 security, MagicEndpoint actively verifies a “user + device” entity. The endpoint provides the IdP server real-time intelligence to monitor the user, device and even the user’s intent. This continuous verification supports zero-trust architecture without burdening the user. Free your users from all remote authentication steps today and step up your security with MagicEndpoint passwordless authentication.
  • 23
    SyncDog Reviews
    If your existing mobile security system is not designed to counteract the latest sophisticated threats that can jailbreak or root your device, you are at risk. Alarmingly, many of the solutions currently available in the market are inadequate in thwarting these advanced threats. Effective mobile security must implement a containerization approach that not only isolates and encrypts the data accessed and stored on the device but also avoids reliance on the Keystore for crypto management. Before you settle on a solution, it’s crucial to challenge any vendor with the following mobile security requirements checklist. First, ensure that there is full encryption of all data on the device and that any data exchanged with the device is protected using AES 256-bit encryption or stronger. Additionally, your security measures should include containerized and encrypted separation of all work-related emails, files, and applications from personal data. It’s also essential that there is encrypted data transfer between applications on the device. Finally, make sure that there is absolutely no use of the KeyStore for storing crypto keys. This comprehensive approach will significantly enhance your mobile security posture.
  • 24
    Zip Security Reviews
    Running a comprehensive security program with Zip requires no specialized knowledge, allowing you to streamline processes with one-click workflows for tasks such as account recovery and deploying CrowdStrike. We equip you with all the necessary tools to take immediate action, ensuring you never fall short of compliance standards. Keep an eye on your system's devices, identities, and third-party tools from a holistic perspective, allowing you to adjust each metric as necessary. Our platform seamlessly integrates top-tier security tools like CrowdStrike, Jamf, and Intune, creating a scalable enterprise security framework that is managed through a unified interface. You can establish uniform security policies across both Windows and macOS devices without the complications of platform-specific setups. Zip serves as your comprehensive partner for procuring, deploying, configuring, and overseeing your entire enterprise security strategy. We take charge of all software acquisitions required to satisfy your customers' expectations, insurance requirements, and compliance obligations, enabling you to focus on what truly matters—growing your business. With Zip, you can experience unparalleled peace of mind knowing your security program is in expert hands.
  • 25
    Rotate Reviews
    Utilize the Rotate cloud security platform to fortify any organization with its flexible hubs and smooth integrations tailored to expand your security capabilities. Enhance your understanding of cyber threats and streamline response efforts by recognizing alerts across all hubs, linking them together, and ranking incidents based on their risk severity. Through Rotate’s XDR, you can effectively synthesize, consolidate, and oversee all hubs. Take advantage of your multi-tenancy control center for conducting vulnerability assessments and executing swift deployments. Manage an unlimited number of clients from a single interface, which simplifies oversight. Equip your business clients with a robust cybersecurity framework while minimizing potential portfolio risks. Rotate safeguards a wide array of organizations in today’s digital-first landscape. Achieve extensive cybersecurity for every employee accessing email or utilizing a device at work. While cyber insurance is a crucial consideration for any business facing the threat of cyber attacks, securing coverage can often be costly. The thorough protection offered by Rotate can significantly mitigate overall insurance expenses, allowing businesses to focus on growth and innovation. This comprehensive approach not only enhances security but also fosters trust with clients and partners.
  • Previous
  • You're on page 1
  • 2
  • Next
MongoDB Logo MongoDB