Best Compliance Software for Microsoft 365 Copilot

RealCISO is a compliance intelligence platform for two audiences: MSPs and MSSPs managing security across multiple clients, and enterprise teams running compliance in-house. MSPs, MSSPs, and security consultants use it to run compliance assessments, manage cyber risk, track remediation, and report to boards — all in one place. Assessments map directly to NIST CSF, SOC 2, NIST 800-171, HIPAA, CIS Controls, CMMC, and 30+ other frameworks. Instead of months of spreadsheet work, clients get a clear picture of where they stand and what to fix — in days. Over 3,000 security providers rely on RealCISO to deliver vCISO services at scale. Built by practitioners. Founded by Brian Haugli — former DoD, former VP & CSO at The Hanover Insurance Group, CISSP, and co-author of the NIST CSF book published by Wiley.

Rhizome serves as an AI regulatory collaborator specifically designed for teams in the life sciences sector. While general AI assistants offer remarkable capabilities, there are distinct requirements for an AI tool that aids in making decisions regarding drugs or devices worth over $100 million. Our agents are strictly limited to referencing facts derived from primary source documents, ensuring that nothing is validated based on agent memory; we assess their performance based on this criterion, and there have been no instances of inaccuracies reported in the past 18 months. The databases that underpin regulatory decisions, including Drugs@FDA, guidance documents, clinicaltrials.gov, and various standards, often exist in formats that are not easily searchable by computers, with a significant amount being image-only PDFs. We have developed the ability to ingest and process all of this information, encompassing over 75 health authority databases across more than 12 markets as of August 2026, with this number continually growing. This equates to over 45 million documents that our agents can query comprehensively. In contrast to a general assistant, which typically references 5 to 10 sources, Rhizome is capable of examining hundreds to thousands of documents, as the essential question is often, "Did we overlook a precedent?" This thorough approach ensures that our users are equipped with the most comprehensive and accurate information possible.