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Description

Site-Identification by Ligand Competitive Saturation (SILCS) produces three-dimensional maps, known as FragMaps, that illustrate how different chemical functional groups interact with a specific target molecule. By revealing the complexities of molecular dynamics, SILCS offers tools that enhance the optimization of ligand scaffolds through both qualitative and quantitative insights into binding pockets, thereby streamlining the drug design process. This approach employs a range of small molecule probes, each featuring diverse functional groups, alongside explicit solvent modeling and accommodating the flexibility of the target molecule to effectively map protein targets. Furthermore, the technique allows researchers to visualize advantageous interactions with the target macromolecule. With these insights, scientists can strategically design improved ligands with functional groups situated in optimal positions for enhanced efficacy. The innovative nature of SILCS represents a significant advancement in the field of medicinal chemistry.

Description

Signals VitroVivo integrates various assay developments, ranging from low throughput to ultra-high-throughput production assays, High Content Screening, and in vivo research, allowing users to access all assay and screening information through a single, comprehensive platform. This system is not only adaptable for individual assay tasks during the development phase, but it is also robust enough to accommodate more complex studies and a wide array of techniques, making it scalable to manage extensive data volumes. Scientists can utilize a consistent and repeatable approach for both data collection and processing protocols, facilitating swift and straightforward structure-activity relationship evaluations for both small and large molecules. Designed to meet specific needs in managing studies, treatments, and samples, this platform enhances the overall efficiency and effectiveness of scientific research, ultimately leading to more innovative discoveries.

API Access

Has API

API Access

Has API

Screenshots View All

Screenshots View All

Integrations

Signals Research Suite

Integrations

Signals Research Suite

Pricing Details

No price information available.
Free Trial
Free Version

Pricing Details

No price information available.
Free Trial
Free Version

Deployment

Web-Based
On-Premises
iPhone App
iPad App
Android App
Windows
Mac
Linux
Chromebook

Deployment

Web-Based
On-Premises
iPhone App
iPad App
Android App
Windows
Mac
Linux
Chromebook

Customer Support

Business Hours
Live Rep (24/7)
Online Support

Customer Support

Business Hours
Live Rep (24/7)
Online Support

Types of Training

Training Docs
Webinars
Live Training (Online)
In Person

Types of Training

Training Docs
Webinars
Live Training (Online)
In Person

Vendor Details

Company Name

SilcsBio

Founded

2012

Country

United States

Website

silcsbio.com/software/

Vendor Details

Company Name

PerkinElmer Informatics

Founded

1937

Country

United States

Website

perkinelmerinformatics.com/products/research/signals-vitrovivo/

Product Features

Product Features

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