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Average Ratings 0 Ratings
Description
ESMFold2 builds upon its predecessor, ESMFold, by establishing a new benchmark in single-sequence structure prediction and facilitating the creation of novel functional proteins via exploration of the latent space within the ESMC model. This advanced model is capable of forecasting high-resolution, all-atom 3D structures of biomolecular complexes straight from the amino acid sequence, and it allows for the incorporation of multiple sequence alignments to improve accuracy on difficult targets. Tailored for predicting structures through both sequence and structure modalities, it employs ESM representations that drive a series of looped folding layers while a diffusion model translates pairwise representations into atomic-resolution outcomes. ESMFold2 excels in predicting protein structures from amino acid sequences, providing detailed structural data, including precise all-atom coordinates for both backbone and side chains, along with confidence metrics and optional distogram predictions for in-depth structural evaluation. Furthermore, its innovative approach enhances the understanding of protein folding dynamics and functional implications, making it a valuable tool for researchers in the field.
Description
Photo51 serves as an online molecular biology platform tailored for the design and examination of DNA and protein sequences. This comprehensive suite facilitates various tasks such as plasmid design, automated feature annotation, virtual cloning, PCR primer development, and simulating agarose gel electrophoresis. Users have the capability to import sequence files and utilize a built-in genome browser to navigate reference genomes, analyze gene views, and export sequences for their projects. Other features offered include the design of guide RNA with PAM visualization, pairwise and multiple sequence alignment, viewing of Sanger chromatograms, protein alignment, and reverse translation capabilities. Additionally, Photo51 fosters collaboration through shared team workspaces and maintains a version history for ongoing projects. The open-access genome browser enhances the exploration of genomic data, while subscription options unlock further editing and analytical functionalities. This platform is specifically designed for researchers, educators, and teams in biotechnology engaged in molecular biology tasks, promoting a streamlined workflow for various scientific inquiries. Overall, Photo51 stands out as a versatile tool that supports the diverse needs of the molecular biology community.
API Access
Has API
Yes
API Access
Has API
No
Integrations
Biohub
No
Mira
No
Python
No
Pricing Details
Free
Free Trial
No
Free Version
Yes
Pricing Details
€5/month
Academic access is €5/month; commercial use is €50/month.
Free Trial
Yes
Free Version
Yes
Deployment
Web-Based
Yes
On-Premises
No
iPhone App
No
iPad App
No
Android App
No
Windows
No
Mac
No
Linux
No
Chromebook
No
Deployment
Web-Based
Yes
On-Premises
No
iPhone App
No
iPad App
No
Android App
No
Windows
Yes
Mac
Yes
Linux
No
Chromebook
No
Customer Support
Business Hours
No
Live Rep (24/7)
No
Online Support
Yes
Customer Support
Business Hours
No
Live Rep (24/7)
No
Online Support
Yes
Types of Training
Training Docs
Yes
Webinars
No
Live Training (Online)
No
In Person
No
Types of Training
Training Docs
Yes
Webinars
No
Live Training (Online)
Yes
In Person
Yes
Vendor Details
Company Name
Biohub
Founded
2016
Country
United States
Website
biohub.ai/models/esmfold2
Vendor Details
Company Name
Fearless League
Founded
2023
Country
Netherlands
Website
fearlessleague.com