Photo51 Description
Photo51 serves as an online molecular biology platform tailored for the design and examination of DNA and protein sequences. This comprehensive suite facilitates various tasks such as plasmid design, automated feature annotation, virtual cloning, PCR primer development, and simulating agarose gel electrophoresis. Users have the capability to import sequence files and utilize a built-in genome browser to navigate reference genomes, analyze gene views, and export sequences for their projects. Other features offered include the design of guide RNA with PAM visualization, pairwise and multiple sequence alignment, viewing of Sanger chromatograms, protein alignment, and reverse translation capabilities. Additionally, Photo51 fosters collaboration through shared team workspaces and maintains a version history for ongoing projects. The open-access genome browser enhances the exploration of genomic data, while subscription options unlock further editing and analytical functionalities. This platform is specifically designed for researchers, educators, and teams in biotechnology engaged in molecular biology tasks, promoting a streamlined workflow for various scientific inquiries. Overall, Photo51 stands out as a versatile tool that supports the diverse needs of the molecular biology community.
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Evo 2
Evo 2 represents a cutting-edge genomic foundation model that excels in making predictions and designing tasks related to DNA, RNA, and proteins. It employs an advanced deep learning architecture that allows for the modeling of biological sequences with single-nucleotide accuracy, achieving impressive scaling of both compute and memory resources as the context length increases. With a robust training of 40 billion parameters and a context length of 1 megabase, Evo 2 has analyzed over 9 trillion nucleotides sourced from a variety of eukaryotic and prokaryotic genomes. This extensive dataset facilitates Evo 2's ability to conduct zero-shot function predictions across various biological types, including DNA, RNA, and proteins, while also being capable of generating innovative sequences that maintain a plausible genomic structure. The model's versatility has been showcased through its effectiveness in designing operational CRISPR systems and in the identification of mutations that could lead to diseases in human genes. Furthermore, Evo 2 is available to the public on Arc's GitHub repository, and it is also incorporated into the NVIDIA BioNeMo framework, enhancing its accessibility for researchers and developers alike. Its integration into existing platforms signifies a major step forward for genomic modeling and analysis.
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Evo Designer
Evo Designer is a cutting-edge tool created by the Arc Institute, harnessing the power of the Evo 2 genomic foundation model to aid in the generation and analysis of DNA sequences. Users can enter nucleotide sequences or select specific organisms, prompting the model to produce relevant DNA sequences tailored to their needs. This platform also offers detailed annotations of coding regions and provides 3D protein visualizations for prokaryotic sequences through ESMFold, enhancing the understanding of protein structures. In addition to these features, Evo Designer evaluates sequences by calculating their perplexity and per-nucleotide entropy, which helps researchers gauge the complexity and variability of the sequences they are working with. The Evo 2 model at the core of this tool has been trained on an impressive dataset of over 9 trillion nucleotides sourced from a wide variety of prokaryotic and eukaryotic genomes. Utilizing a sophisticated deep learning architecture, it models biological sequences with single-nucleotide precision and boasts a context window that can extend up to 1 million tokens, thereby ensuring high accuracy in sequence representation and analysis. This combination of features makes Evo Designer an invaluable resource for genetic research and exploration.
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Pricing
Pricing Starts At:
€5/month
Pricing Information:
Academic access is €5/month; commercial use is €50/month.
Free Version:
Yes
Free Trial:
Yes
Integrations
No Integrations at this time
Company Details
Company:
Fearless League
Year Founded:
2023
Headquarters:
Netherlands
Website:
fearlessleague.com
Media
Genome library listing local and downloadable reference genomes.
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Product Details
Platforms
Web-Based
Windows
Mac
Types of Training
Training Docs
Live Training (Online)
In Person
Training Videos
Customer Support
Online Support
Photo51 Features and Options
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